儿童癫痫的精准治疗  

Precision treatment in pediatric epilepsy

作　　者：石秀玉[1] 胡琳燕[1] 韩芳 邹丽萍[1] SHI Xiuyu;HU Linyan;HAN Fang;ZOU Liping(Department of Pediatrics,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]中国人民解放军总医院儿科医学部第一医学中心儿内科,北京100853

出　　处：《临床儿科杂志》2022年第3期170-176,共7页Journal of Clinical Pediatrics

基　　金：国家自然科学基金面上项目(No.81771389)。

摘　　要：癫痫是儿童时期最常见且危害最大的神经系统疾病之一,抗癫痫药是主要的治疗方法,但在过去几十年,人们对癫痫的病因了解不多,因此主要是根据癫痫发作类型进行选药,治标不治本。近年来随着检测工具和手段的进步,越来越多的癫痫患儿能够找到癫痫病因,针对病因进行治疗能达到标本兼治的目的,儿童癫痫的治疗正步入精准治疗时代。文章根据2017年国际抗癫痫联盟新的癫痫病因分类,总结不同病因的检测方法以及相应的精准治疗,以期提高癫痫的治疗效果。Epilepsy is one of the commonest and the most devastating neurological diseases in childhood,and antiepileptic drugs are the main treatment method.In the past few decades,because the causes of epilepsy were not well understood,drug selection was largely based on the type of seizure,treating only the symptoms rather than the root causes.In recent years,with new tools and means,the diagnosis of the cause of epilepsy has dramatically improved,and the treatment for the cause can achieve the purpose of treating both the symptoms and root causes.The treatment of childhood epilepsy is entering the era of precision treatment.According to the new classification of epilepsy causes published in 2017 by International League Against Epilepsy(ILAE),this paper summarizes new available tests for making diagnoses in each of the etiological categories in the ILAE classification and the corresponding precision treatment.

关 键 词：癫痫 儿童 病因 精准治疗 

分 类 号：R742.1[医药卫生—神经病学与精神病学]