Urban-rural disparities in mild cognitive impairment and its functional subtypes among community- dwelling older residents in central China  

作　　者：Dan Liu Lin Li Lina An Guirong Cheng Cong Chen Mingjun Zou Bo Zhang Xuguang Gan Lang Xu Yangming Ou Qingming Wu Ru Wang Yan Zeng 

机构地区：[1]Brain Science and Advanced Technology Institute,Wuhan University of Science and Technology,Wuhan,Hubei,China [2]Xiangyang Center for Disease Control and Prevention,Xiangyang,Hubei,China [3]Tianyou Hospital,Wuhan University of Science and Technology,Wuhan,Hubei,China [4]China Resources and WISCO General Hospital,Wuhan,Hubei,China

出　　处：《General Psychiatry》2021年第5期23-30,I0005,共9页综合精神医学（英文）

基　　金：The study was funded by the National Natural Science Foundation of China(71774127,81771488,81870901).

摘　　要：background Substantial variations in the prevalence of mild cognitive impairment(MCI)and its subtypes have been reported,although mostly in geographically defined developed countries and regions.Less is known about MCI and its subtypes in rural areas of less developed central China.Aims The study aimed to compare the prevalence of MCI and its subtypes in residents aged 65 years or older in urban and rural areas of Hubei Province,China.Methods Participants aged 65 years or older were recruited between 2018 and 2019.Inperson structured interviews and clinical and neuropsychological assessments were performed at city health community centres and township hospitals.results Among 2644 participants without dementia,735 had MCI,resulting in a prevalence of 27.8%for total MCI,20.9%for amnestic MCI(aMCI)and 6.9%for non-amnestic MCI(naMCI).The prevalence of MCI in urban and rural areas was 20.2%and 44.1%,respectively.After adjusting for demographic factors,the prevalence of total MCI,aMCI and naMCI differed significantly between rural and urban areas(adjusted odds ratio(OR)2.10,1.44 and 3.76,respectively).Subgroup analysis revealed an association between rural socioeconomic and lifestyle disadvantage and MCI and its subtypes.Conclusions Our findings suggest that the prevalence of MCI among urban residents in central China is consistent with that in other metropolis areas,such as Shanghai,but the prevalence in rural areas is twice that in urban areas.Prospective studies and dementia prevention in China should focus on rural areas.

关 键 词：IMPAIRMENT prevention DISADVANTAGE 

分 类 号：R749[医药卫生—神经病学与精神病学]