The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation  

作　　者：Adam Khalifa Mohsen Zaeimbashi Tony X.Zhou Seyed Mahdi Abrishami Neville Sun Seunghyun Park TamaraŠumarac Jason Qu Inbar Zohar Amir Yacoby Sydney Cash Nian X.Sun 

机构地区：[1]Department of Neurology,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA [2]Department of Electrical and Computer Engineering,Northeastern University,Boston,MA,USA [3]Research Laboratory of Electronics,Massachusetts Institute of Technology,Cambridge,MA,USA [4]Department of Physics,Harvard University,Cambridge,MA,USA [5]Department of Chemical and Biological Physics,Weizmann Institute of Science,Rehovot,Israel

出　　处：《Microsystems & Nanoengineering》2021年第6期97-106,共10页微系统与纳米工程（英文）

基　　金：This work was supported by the National Science Foundation under ECCS1533484 and NIH NINDS(UF1NS107694);Diamond sample fabrication was performed at the Center for Nanoscale Systems(CNS)at Harvard University,a member of the National Nanotechnology Coordinated Infrastructure;which is supported by the NSF under ECCS-1541959.

摘　　要：Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions.Despite its remarkable success,the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions.Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact.Here,we demonstrate a novel microfabricated solenoid inductor(80µm×40µm)with a magnetic core that can activate neuronal tissue.The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications.

关 键 词：MAGNETIC NEURAL OVERCOME 

分 类 号：R749[医药卫生—神经病学与精神病学]