The retinal function imager and clinical applications  

作　　者：Daniel Su Sunir Garg 

机构地区：[1]The Retina Service of Wills Eye Hospital,Mid Atlantic Retina,840 Walnut Street,Suite 1020,Philadelphia,PA 19107,USA

出　　处：《Eye and Vision》2018年第1期191-195,共5页眼视光学杂志（英文）

摘　　要：Background:The Retinal Function Imager(RFI)provides in vivo and noninvasive imaging of both the retinal structure and function.Review:The RFI can create capillary perfusion maps,measure blood flow velocity,and determine metabolic function including blood oximetry.It can aid clinical diagnosis as well as assess treatment response in several retinal vascular diseases including diabetic retinopathy.Blood flow velocity abnormalities have also been implicated in disease such as age-related macular degeneration and require further investigation.Compared with optical coherence tomography angiography,the RFI produces capillary maps of comparable image quality and wider field of view but it is unable to provide depth-resolved information and has longer image acquisition time.Currently,functional imaging using blood oximetry has limited applications and additional research is required.Conclusion:The RFI offers noninvasive,high-resolution imaging of retinal microvasculature by creating capillary perfusion maps.In addition,it is capable of measuring retinal blood velocity directly and performs functional imaging with retinal blood oximetry.Its clinical applications are broad and additional research with functional imaging may potentially lead to diagnosis of diseases and their progression before anatomic abnormalities become evident,but longer image acquisition times may limit its clinical adoption.

关 键 词：Retinal function imager Retinal blood flow Blood flow velocity OXIMETRY Noninvasive imaging RETINA 

分 类 号：R73[医药卫生—肿瘤]