Current review of Excimer laser Trabeculostomy  

作　　者：Georges M.Durr Marc Töteberg-Harms Richard Lewis Antonio Fea Paola Marolo Iqbal Ike K.Ahmed 

机构地区：[1]Department of Ophthalmology,Universitéde Montréal,Montreal,Quebec,Canada [2]Department of Ophthalmology,Centre Hospitalier Universitaire de Montréal(CHUM),1051 Rue Sanguinet,Montreal H2X 3E4,Quebec,Canada [3]Department of Ophthalmology,University Hospital Zurich,Zurich,Switzerland [4]Sacramento Eye Consultants,Sacramento,California,USA [5]Struttura Complessa Oculistica,Cittàdella Salute e della Scienza di Torino,Dipartimento di Scienze Chirurgiche,Universitàdegli Studi di Torino,Torino,Italy [6]Department of Ophthalmology&Vision Sciences,University of Toronto,Toronto,Ontario,Canada

出　　处：《Eye and Vision》2020年第1期232-240,共9页眼视光学杂志（英文）

摘　　要：Background:Excimer laser trabeculostomy(ELT)is a microinvasive glaucoma surgery(MIGS)that creates multiple laser channels through the trabecular meshwork using a cold laser system,which minimizes tissue fibrosis and aids in bypassing the main area of resistance to aqueous outflow.The purpose of this review is to evaluate the current body of evidence surrounding ELT in terms of efficacy and review the safety profile of the procedure.Main text:Studies screened had to show clear inclusion and exclusion criteria as well as well-defined outcome measures.PubMed,MEDLINE,EMBASE and the Cochrane Controlled Trial Database were searched.Preferred Reporting Items of Systematic Reviews(PRISMA)guidelines were used to assess for study quality and for any bias.Sixty-four articles were initially identified with 18 meeting preliminary screening criteria.Ultimately,8 studies met inclusion criteria and 2 additional non-referenced publications were also included:1 randomized control trial,4 prospective case series and 5 retrospective studies.Overall studies showed moderate intraocular pressure(IOP)lowering of between 20%and 40%from baseline without medication washout and mostly a decrease in glaucoma medications with few complications.Conclusion:Current literature shows a significant IOP-lowering effect of ELT with a favorable safety-profile in standalone cases or combined with cataract surgery.Limitations to these studies are the lack of controls and washout IOP.Overall,ELT is an attractive MIGS option that does not require any residual device remaining in the angle.

关 键 词：Excimer laser trabeculostomy TRABECULOTOMY ELT Intraocular pressure GLAUCOMA MIGS CATARACT 

分 类 号：R779.6[医药卫生—眼科]