EFFECTS OF RED LIGHT AT 640nm FROM LIGHT EMITTING DIODES ON THE RESPIRATORY BURST OF HUMAN NEUTROPHILS  

作　　者：MIN WU LING ZHU BINA HU TIMON CHENG-YI LIU DONG-LIANG RONG TONG-SHENG CHEN 

机构地区：[1]Laboratory of Laser Sports Medicine South China Normal University Guangzhou,GD 510006,China [2]MOE Key Laboratory of Laser Life Science South China Normal University,Guangzhou,GD 510631,China

出　　处：《Journal of Innovative Optical Health Sciences》2008年第2期285-294,共10页创新光学健康科学杂志（英文）

基　　金：supported by National Science Foundation of China(60478048,60178003 and 69778003);the Opening Project of MOE Key Laboratory of Laser Life Science,South China Normal University,Guangzhou 510631,China.

摘　　要：Photobiomodulation(PBM)has been reported to have effects on respiratory burst of polymorphonuclear neutrophils(PMNs),but little focus was on the individual differences of human PMNs.The latter was investigated in this study.The PMNs were isolated from peripheral blood of 13 volunteers(10 ordinary persons,3 athletes)and treated by red light(640±15 nm)from light emitting diodes(RLED)at 50,100,300,500 and 1000 J/m^(2)for 100 seconds,respectively.Blood samples of athletes were extracted at different running stages in 10 km non-interrupted long-distance running,before running,1 hour after running began,just finishing the running,resting for 1 hour and 2 hours after running.The PMN respiratory burst was assessed by the nitroblue tetrazolium test.It was found that there were three types of RLED PBM on the respiratory burst of 3 types of PMNs,respectively,inducing for the subactivated PMNs,inhibiting for the overactivated PMNs and none for the PMNs in homeostasis.It was then concluded that there may be RLED PBM on dysfunctional human PMNs while none on those in homeostasis,and RLED at 300 J/m^(2)for 100 seconds may have bi-direction modulation on PMN respiratory burst.

关 键 词：Polymorphonuclear neutrophils PHOTOBIOMODULATION HOMEOSTASIS 

分 类 号：R36[医药卫生—病理学]