胸腺神经内分泌肿瘤的诊疗进展  

Progress in diagnosis and treatment of thymic neuroendocrine tumors

作　　者：张家齐[1] 陈野野[1] 周梦馨 黄诚[1] 张晔[1] 郭超[1] 李单青 ZHANG Jiaqi;CHEN Yeye;ZHOU Mengxin;HUANG Cheng;ZHANG Ye;GUO Chao;LI Shanqing(Department of Thoracic Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100730,P.R.China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院胸外科,北京100730

出　　处：《中国胸心血管外科临床杂志》2022年第4期488-496,共9页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：吴阶平医学基金会资助课题(FW-HXKT2019102802095)。

摘　　要：胸腺神经内分泌肿瘤是一种罕见疾病,具有生物学侵袭性,预后较差;其临床表现不典型,部分肿瘤可异位分泌促肾上腺皮质激素,引起内分泌症状。由于发病率低、异质性强,临床诊疗难度大,新型治疗方案难以突破。早期完整手术切除是有效治疗手段。对于晚期肿瘤,期待新药物的临床试验,提高患者生存预后。Thymic neuroendocrine tumors(TNETs)are a series of rare diseases with aggressive biology and poor prognosis.Clinical manifestations of TNETs are atypical,and ectopic secretion of adrenocorticotropic hormone can be found in some cases,resulting in associated endocrine symptoms.Due to the low morbidity and strong heterogeneity,it’s difficult to diagnose,treat and obtain new treatment regimen.Early complete surgical resection is an effective treatment.For advanced cancer,clinical trials of new drugs are expected to improve the survival of patients.

关 键 词：胸腺 神经内分泌肿瘤 进展 综述 

分 类 号：R736.3[医药卫生—肿瘤]