Huge gastric plexiform fibromyxoma presenting as pyemia by rupture of tumor:A case report  

作　　者：Rui Zhang Li-Gang Xia Kai-Bin Huang Nan-Di Chen 

机构地区：[1]The Second Clinical Medical College,Shenzhen People’s Hospital,Jinan University,Shenzhen 518020,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2022年第7期2253-2260,共8页世界临床病例杂志

摘　　要：BACKGROUND Plexiform fibromyxoma(PF)is a rare mesenchymal tumor,with limited case reports worldwide.Common clinical symptoms are abdominal discomfort and bleeding signs,which frequently present slow-onset in reported cases.Herein,we report a case of gastric PF presenting as acute onset and with pyemia accompanying tumor rupture.We resected the tumor as well as the distal gastric,bulbus duodeni and gallbladder for treatment in emergency surgery.Notably,before the onset of the disease,the patient received coronavirus disease 2019(COVID-19)vaccines.CASE SUMMARY A 26-year-old man was admitted to our hospital,due to abdominal pain and fever after having received COVID-19 vaccines.Laboratory examination indicated severe sepsis.Computed tomography scan revealed a large mass in the abdomen.Deformation of the gastrointestinal tract was seen during gastroscopy.After failure of anti-infective treatment and symptoms of shock developed,he received an emergency surgery.We found a huge and partly ruptured mass,with thick purulence.Microscopically,the mass was composed of spindle cells with clarified cytoplasm,accompanied by myxoid stroma and arborizing blood vessels.Immunohistochemistry showed the tumor cells as positive for smooth muscle actin and succinate dehydrogenase subunit B but negative for DOG-1 and CD117.Finally,the patient was diagnosed with gastric PF and discharged from the hospital.CONCLUSION Gastric PF manifesting as tumor rupture combined with pyemia is rare.Timely surgery is critical for optimal prognosis.

关 键 词：Gastric plexiform fibromyxoma Clinical manifestations SEPSIS Emergency surgery Pathology COVID-19 vaccines Case report 

分 类 号：R735.2[医药卫生—肿瘤] R459.7[医药卫生—临床医学]