Effects of physical exercise on the quality-of-life of patients with haematological malignancies and thrombocytopenia:A systematic review and meta-analysis  

作　　者：Yu-Pei Yang Shuang-Jun Pan Shu-Lin Qiu Tao-Hsin Tung 

机构地区：[1]Department of Hematology,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Linhai 317000,Zhejiang Province,China [2]Department of Neurosurgery,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Linhai 317000,Zhejiang Province,China [3]Institute for Hospital Management,Tsing Hua University,Shenzhen 518055,Guangdong Province,China [4]Evidence-Based Medicine Center,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Linhai 317000,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2022年第10期3143-3155,共13页世界临床病例杂志

摘　　要：BACKGROUND Annually,there are an estimated 1187000 new patients worldwide diagnosed with haematological malignancies.Effective strategies are needed to alleviate side effects and prevent the physical and psychosocial degeneration of patients in active treatment for haematological malignancies.AIM To explore the effects of physical exercise on quality of life(Qo L)of patients with haematological malignancies and thrombocytopenia.METHODS Cochrane Library,Pub Med and Embase were searched for all relevant articles reporting randomized controlled trials(RCTs)that were published up to 31 July 2021.Two authors independently selected articles in accordance with the inclusion criteria,evaluated their quality,and collected information.Any controversy was resolved through discussion with a third senior author.The PRISMA 2009 checklist was followed.RESULTS Seven RCTs were selected in the systematic review and three were included in the final meta-analysis.There were significant differences in Qo L between physical exercise groups[mean score difference=8.81;95%confidence interval(CI):1.81-15.81,P=0.01],especially in emotional functioning(mean score difference=12.34;95%CI:4.64-20.04,P=0.002)and pain(mean score difference=–12.77;95%CI:-3.91 to-21.63,P=0.005).CONCLUSION Physical exercise has clinical effects on Qo L and improves emotional function and pain indices of patients with haematological malignancies and thrombocytopenia.

关 键 词：Haematological malignancies THROMBOCYTOPENIA EXERCISE QUALITY-OF-LIFE Systematic review META-ANALYSIS 

分 类 号：R733[医药卫生—肿瘤] R558.2[医药卫生—临床医学]