原发性特应性疾病的发生机制研究进展  

Progress in the pathogenesis of primary atopic diseases

作　　者：朱晓娜 夏宇[1] Zhu Xiaona;Xia Yu(Department of Rheumatology and Immunology,Shenzhen Children′s Hospital,Shenzhen 518000,China)

机构地区：[1]深圳市儿童医院风湿免疫科,深圳518000

出　　处：《中华实用儿科临床杂志》2022年第6期478-480,共3页Chinese Journal of Applied Clinical Pediatrics

基　　金：广东省高水平临床重点专科(深圳市配套建设经费)资助(SZGSP012);深圳市三名工程项目(SZSM201812002)。

摘　　要：既往特应性疾病被认为是环境与遗传易感性共同作用的复杂多基因病,但近年来一些单基因变异所致的原发性特应性疾病逐渐引起研究者的重视。现对其发病机制及临床特征进行综述,以期提高临床医师对该类疾病的认识。Atopic diseases used to be considered as complex polygenic diseases with the interaction of environmental factors and genetic susceptibility.In recent years,primary atopic diseases caused by single-gene mutations have been well concerned.This study aims to review the pathogenesis and clinical characteristics of atopic diseases,thus strengthening the understanding.

关 键 词：原发性特应性疾病 单基因 过敏 

分 类 号：R593.1[医药卫生—内科学]