黄河三角洲地区居民膳食模式与胃粘膜萎缩的相关性研究  

Relationship between dietary patterns and gastric mucosal atrophy of residents in the Yellow River Delta

作　　者：胡延华 陈丽君[1] 王秀华[1] 马爱国[2] 范俊青[1] 高桃[1] HU Yan-hua;CHENLi-jun;WANGXiu-hua;MAAi-guo;FANJun-qing;GAO Tao(The Affiliated Hospital of Binzhou Medical University,Binzhou,Shandong 256603,China;不详)

机构地区：[1]滨州医学院附属医院,山东滨州256603 [2]青岛大学公共卫生学院

出　　处：《现代预防医学》2022年第7期1196-1201,共6页Modern Preventive Medicine

基　　金：山东省医药卫生科技发展计划(2017WS549)。

摘　　要：目的 研究黄河三角洲地区居民膳食模式与胃粘膜萎缩的相关性。方法 采用横断面研究方法,选取2020年5月—2021年6月黄河三角洲地区具有代表性的4所三级综合医院内镜室完成胃镜检查的583名患者作为研究对象;使用一般资料调查表、食物频率法问卷收集研究对象的基本资料和过去1年的食物摄入情况;采用主成分分析(PCA)法提取膳食模式;采用多因素非条件logistic回归分析膳食模式与胃粘膜萎缩的相关性。结果 研究对象的文化程度、盐的摄入量、饮酒情况、胃病家族史、幽门螺旋杆菌、睡眠情况、焦虑情况和抑郁情况对胃粘膜萎缩的发生有显著影响(P<0.05)。共提取5种膳食模式,累计因子贡献率为39.267%。Logistic回归分析结果显示,调整混杂因素后,高钠高脂膳食模式与胃粘膜萎缩呈正相关,会显著增加胃粘膜萎缩发生的风险(趋势性P=0.025);平衡膳食模式与胃粘膜萎缩呈负相关,会显著降低胃粘膜萎缩发生的风险(趋势性P=0.007);茶膳食模式与胃粘膜萎缩呈正相关,会增加胃粘膜萎缩发生的风险,但这种相关性并不显著(P=0.132)。结论 黄河三角洲地区居民的膳食模式与胃粘膜萎缩是相关的,应指导本地区人群建立良好健康平衡膳食模式,减少胃粘膜萎缩的发病率,进而减少胃癌的发生。Objective To explore the association between gastric mucosa atrophy and dietary pattern in the Yellow River Delta. Methods Between May 2020 and June 2021, one cross-sectional study was conducted in four tertiary general hospitals in Yellow River Delta. A total of 583 patients who underwent gastroscopy in endoscopy rooms were enrolled in this study. General data questionnaire and food frequency questionnaire were used to collect the basic information and food intake of the subjects in the past one year. Dietary patterns were extracted by principal component analysis(PCA). The correlation between dietary pattern and gastric mucosa atrophy was analyzed by multi-factor non-conditional logistic regression. Results The educational level, salt intake, alcohol consumption, family history of gastric diseases, Helicobacter pylori, sleep, anxiety and depression had significant influence on the occurrence of gastric atrophy(P<0.05). A total of five dietary patterns with a cumulative factor contribution rate of 39.267% were extracted. Logistic regression analysis showed that after adjusting confounding factors, high-sodium and high-fat dietary pattern was positively associated with gastric mucosal atrophy and would significantly increase the risk of gastric mucosal atrophy(P;=0.025). Healthy dietary pattern was negatively correlated with gastric mucosa atrophy, and significantly reduced the risk of gastric mucosa atrophy(P;=0.007). Tea dietary pattern was positively associated with gastric mucosa atrophy, which increased the risk of gastric mucosa atrophy, but the correlation was not significant(P=0.132). Traditional and modern fast-food diets were not associated with gastric mucosal atrophy. Conclusion The dietary pattern of residents in the Yellow River Delta is associated with gastric mucosa atrophy. Guidance should be given to the local population to establish a healthy and balanced dietary pattern, and reduce the incidence of gastric mucosa atrophy and gastric cancer.

关 键 词：黄河三角洲地区 膳食模式 胃粘膜萎缩 主成分分析法 相关性分析 

分 类 号：R151.4[医药卫生—营养与食品卫生学] R573.32[医药卫生—公共卫生与预防医学]