Pointing fingers at blood contact:mechanisms of subventricular zone neural stem cell differentiation  

作　　者：Subash C.Malik Yu-Hsuan Chu Christian Schachtrup 

机构地区：[1]Institute of Anatomy and Cell Biology,Faculty of Medicine,University of Freiburg,Freiburg,Germany [2]Faculty of Biology,University of Freiburg,Freiburg,Germany [3]Center for Basics in NeuroModulation(NeuroModulBasics),Faculty of Medicine,University of Freiburg,Freiburg,Germany

出　　处：《Neural Regeneration Research》2023年第1期137-138,共2页中国神经再生研究（英文版）

基　　金：support from the German Research Foundation Grants SCHA 1442/8-1, and 1442/9-1 to CS

摘　　要：The limited ability of the central nervous system(CNS)to regenerate in adult mammals after injury or disease is a significant problem.Intriguingly,neural stem/progenitor cells(NSPCs)offer great promise for regenerating the CNS.Endogenous or transplanted NSPCs contribute to repair processes,but their differentiation and function are abnormal in CNS injury and disease.The main reasons for these abnormalities are changes in the extracellular environment in the injured CNS that affect signaling pathways and transcriptional regulation in NSPCs.

关 键 词：VENTRICULAR neural INJURY 

分 类 号：R741[医药卫生—神经病学与精神病学]