基于先进材料的纸基传感器在多毒素联合检测中的应用  

Application in Paper-based Sensors Based on Smart Materials for Joint Detection of Mycotoxins

作　　者：熊玥 郭婷[1,2] 周莹 周鸿媛 李泓霖[1] 张宇昊 马良 Xiong Yue;Guo Ting;Zhou Ying;Zhou Hongyuan;Li Honglin;Zhang Yuhao;Ma Liang(College of Food Science,Southwest University,Chongqing 400715;Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing,Chongqing 400715)

机构地区：[1]西南大学食品科学学院,重庆400715 [2]川渝共建特色食品重庆市重点实验室,重庆400715

出　　处：《中国食品学报》2022年第4期408-417,共10页Journal of Chinese Institute Of Food Science and Technology

基　　金：国家自然科学基金项目(32072137);中央高校基本科研业务费重点项目(XDJK2020B044);重庆市留学归国人员创新创业计划项目(cx2018032)。

摘　　要：农产品、食品和饲料等常因霉菌侵染而被多种真菌毒素污染,研发高通量真菌毒素快速检测产品是热点研究领域之一。目前主流的真菌毒素快检产品中,传统纸基传感器大多以胶体金作为信号标记物用于单一毒素检测,获得信息相对有限。多毒素纸基传感器常常偶联多种真菌毒素抗原,成本更低,耗时更短,然而检测灵敏度因测试样液量变化而受到影响。近年来,在真菌毒素快检领域引入贵金属纳米粒子、量子点、碳纳米材料、上转换粒子、镧系金属纳米粒子等先进材料,可以改善传感器的检测性能。笔者总结了多毒素纸基传感器的检测原理和组成,综述近年来文献报道中基于先进材料的纸基传感器同时检测多种真菌毒素的研究与应用,分析多毒素纸基传感器未来的研究趋势,以期为多种真菌毒素快速高通量检测相关研究提供参考。Agricultural products, food and feed are often contaminated by many mycotoxins. The development of high-throughput mycotoxin rapid detection products, which are used to detect multiple toxins is one of the key directions. Among the current mainstream rapid detection products, traditional paper-based sensors with colloidal gold as signal markers are mostly used to detect a single toxin, with limited information and low sensitivity. The multi-toxin paper-based sensor uses multi-toxins to couple multi-antigens, which is lower in cost and time-consuming, but the detection sensitivity is affected by the change of the test sample liquid volume. In recent years, paper-based sensors constructed with advanced materials such as precious metal nanoparticles, quantum dots, carbon nanomaterials, up-conversion particles,lanthanide metal nanoparticles, which can improve the performance of multi-toxin paper-based sensors. And they have gradually become a research for hot spot of rapid detection of multiple mycotoxins. The author summarized the detection principle and composition of multiplexed paper-based sensors, and then reviewed the applications of paper-based sensors based on advanced materials reported in the past years for simultaneous detection of multiple mycotoxins, with a view to rapid and joint detection of multiple mycotoxins.

关 键 词：多毒素 试纸条 纸基传感器 纳米材料 快速检测 

分 类 号：TS207[轻工技术与工程—食品科学] S816.17[轻工技术与工程—食品科学与工程] TP212[农业科学—饲料科学]