结节性脆发症1例  

A case of trichorrhexis nodosa

作　　者：肖沙[1] 高涛[1] 刁庆春[1] XIAO Sha;GAO Tao;DIAO Qingchun(Chongqing Traditional Chinese Medicine Hospital,Chongqing Clinical Research Center for Dermatology,Chongqing 400011,China)

机构地区：[1]重庆市中医院皮肤科重庆市皮肤病学临床医学研究中心,重庆400011

出　　处：《皮肤性病诊疗学杂志》2022年第2期143-146,共4页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：重庆市皮肤病临床医学研究中心项目(cstc2015yfpt_gcjsyjzx120014)。

摘　　要：报告1例结节性脆发症。患者女,27岁,头发白色结节、易断17年。皮肤专科情况:头发稀少,发质干枯,见较多沿毛干密集分布的细小颗粒样白色结节,轻拉头发易断裂。皮肤镜检查:病变区呈中间粗两端细的白色结节状改变。光镜检查:毛小皮不连续,干燥无光泽,较多断裂的丝状纤维向外展开,像两把“扫帚”或“漆刷”末端相互插入。扫描电镜检查:病变中央毛小皮消失,皮质层纤维断裂,粗细不均,部分向外展开或卷曲。诊断:结节性脆发症。We report a case of trichorrhexis nodosa.A 27-year-old female presented with white nodules of hair that were easily broken for 17 years.Dermatological examination showed that the hair was sparse,dry,and there were many tiny granular white nodules densely distributed along the hair shaft,and the hair was easily broken when pulled lightly.Dermoscopy examination showed that the lesions were white nodules with thick middle and thin ends.Optical microscopic examination showed that the hair cuticle was discontinuous,dry and dull,and many broken filamentous fibers spread outward,like two“brooms”or“paint brushes”inserted into each other.Scanning electron microscopic examination showed that the central hair cuticle disappeared,the cortical fibers were broken,uneven in thickness,and some of them expanded or curled outward.The diagnosis was trichorrhexis nodosa.

关 键 词：结节性脆发症 获得性 扫描电镜 

分 类 号：R73[医药卫生—肿瘤]