宽郁舒气方联合乳清蛋白改善乳腺癌患者术后生存状况的作用  

Effects of Kuanyu Shuqi prescription combined with whey protein on the prognosis of breast cancer patients

作　　者：王静[1] 郭萍利[1] 马娟 史博慧 WANG Jing;GUO Pingli;MA Juan;SHI Bohui(Breast Surgery Department,First Affiliated Hospital of Xi’an Jiaotong University,Xi'an,Shaanxi,710061,China)

机构地区：[1]西安交通大学医学院第一附属医院乳腺外科,陕西西安710061

出　　处：《肿瘤药学》2022年第2期263-266,共4页Anti-Tumor Pharmacy

摘　　要：目的研究乳腺癌患者术后使用宽郁舒气方和乳清蛋白的作用。方法将我院收治的90例乳腺癌患者按随机数字表法分为对照组和观察组,各45例。两组患者均行乳腺癌根治术,术后采用不同的营养支持方案进行干预,对照组给予常规营养+乳清蛋白,观察组在对照组的基础上加用宽郁舒气方。比较两组患者营养状况、生活质量、心理负面情绪等方面的差异。结果干预后,观察组患者体质指数(BMI)、上臂肌围(MAMC)、血清血红蛋白(Hb)水平、白蛋白(ALB)水平分别为(18.4±2.8)kg·m^(-2)、(28.7±4.5)cm、(40.5±4.2)g·L^(-1)、(46.4±4.1)g·L^(-1),改善程度均优于对照组,差异有统计学意义(P<0.05);观察组患者SAS评分和SDS评分[(37.68±2.16)、(38.68±1.65)]均低于对照组[(57.75±2.15)、(42.58±2.89)],差异有统计学意义(P<0.05),情绪改善效果更为明显;观察组患者生活质量评分亦明显高于对照组(P<0.05)。结论宽郁舒气方联合乳清蛋白可改善乳腺癌患者术后生存状况,值得临床推广应用。Objective To study the effects of Kuanyu Shuqi prescription and whey protein on postoperative breast can‑cer patients.Methods Ninety patients with breast cancer admitted to the First Affiliated Hospital of Xi′an Jiaotong University were divided into the control group and the observation group according to the random number table method,with 45 cases in each group.Nutritional support was given after radical mastectomy.The nutrition support program was conventional nutrition+whey protein for the control group,and was conventional nutrition+whey protein+Kuanyu Shuqi recipe for the observation group.Record the changes of nutritional status indicators,such as body mass index(BMI),mid-arm muscle circumference(MAMC),serum hemoglobin(Hb),albumin(ALB)and so on.Assess the emotional state of patients with the self-rating depression scale(SDS)and self-rating anxiety scale(SAS).Compare the differences in nutritional status,quality of life,and negative psychological emotions of patients between the two groups.Results After intervention,the BMI,MAMC,Hb,and ALB of patients in the observation group were(18.4±2.8)kg·m^(-2),(28.7±4.5)cm,(40.5±4.2)g·L^(-1),(46.4±4.1)g·L^(-1),repsectively.The observation group showed greater improvement in nutritional status than the control group(P<0.05).The SAS score was(37.68±2.16)and the SDS score was(38.68±1.65)in the observation group,and was respectively(57.75±2.15)and(42.58±2.89)in the control group.The emotional state of patients was improved much greater in the observation group than in the control group(P<0.05).The quality of life score of the observation group was significantly higher than that of the control group(P<0.05).Conclusion Kuanyu Shuqi prescription combined with whey protein can improve the survival status of breast cancer patients after surgery.

关 键 词：宽郁舒气方 乳清蛋白 乳腺癌 营养支持 生活质量 

分 类 号：R737.9[医药卫生—肿瘤]