Comparison of the effect of cinnamon and lentil extract on learning,short-term memory and pain tolerance in rats  

作　　者：Leila Ghassemifard Narjes Khavasi Hossein Mostafavi 

机构地区：[1]Department of Physiology,School of Medicine,Zanjan University of Medical Sciences,Zanjan 4513956111,Iran [2]Department of Persian Medicine,School of Medicine,Zanjan University of Medical Sciences,Zanjan 4513956111,Iran

出　　处：《Aging Communications》2022年第2期13-17,共5页衰老通讯

摘　　要：Background:Learning,memory disorders,and pain,especially Alzheimer’s,are some of the factors that affect today’s societies and disrupt their lives.On the other hand,the type of diet with hot and cold temperament is associated with memory and pain;therefore,inthis study,the effect of Cinnamon extract(hot temperament)and Lentil extract(cold temperament)on pain and memory was investigated.Methods:Animals were randomly divided into three groups including the control group,a group that received Cinnamon extract,and rats who were treated with lentil extract at a dose of 260 intraperitoneally.Then,24 hours after the last injection,pain and memory tests were performed for each.Results:The results of the Passive avoidance test(PAT)(shuttle box)showed that the latency time in going to the dark chamber in the group that received Lentils compared to cinnamon was significantly reduced(P<0.01).The retention time of animals in the dark chamber was significantly increased in the group that received Lentil extract in comparison with the Cinnamon group(P<0.001).The number of visits to the dark compartment significantly decreased in the group that received Cinnamon extract compared to the Lentil group(P<0.01).Pain test results also showed that the Lentil group had significantly less pain tolerance than the Cinnamon group(P<0.001).Conclusion:In this study,Cinnamon compared to Lentil increased memory and pain tolerance;therefore,it can be said that hot and cold temperament probably affects memory and learning as well as the level of pain tolerance.

关 键 词：CINNAMON LENTIL MEMORY PAIN 

分 类 号：R28[医药卫生—中药学]