Bilateral diffuse uveal melanocytic proliferation associated with endometrial carcinoma–multimodal imaging analysis  

作　　者：Zhi-Peng Cai Hong Zhang Jin-Jing Zhang Chuan-Hong Jie Fang-Tian Dong 

机构地区：[1]Eye Hospital,China Academy of Chinese Medical Sciences,Beijing 100040,China [2]Department of Ophthalmology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China

出　　处：《International Journal of Ophthalmology(English edition)》2022年第7期1209-1213,共5页国际眼科杂志（英文版）

摘　　要：Dear Editor,We present a rare case of bilateral diffuse uveal melanocytic proliferation (BDUMP) associated with endometrial carcinoma.BDUMP is a rare paraneoplastic ocular syndrome with generally poor prognosis.Typical features include:1) multiple subtle,round,or oval red patches in the retinal pigment epithelium (RPE) of the posterior fundus;2)multifocal areas of early hyperfluorescence corresponding to these patches;3) development of multiple,slightly elevated pigmented and non-pigmented uveal melanocytic tumours with diffuse thickening of the uveal tracts;4) exudative retinal detachment;5) rapid progression of cataracts.These patches progressively increase in size and merge into the giraffe-like pattern characteristic of BDUMP.Additional signs may be present,including cysts in the ciliary body and iris,dilated episcleral vessels,and a shallow anterior chamber.

关 键 词：ELEVATED EPITHELIUM MODAL 

分 类 号：R739.7[医药卫生—肿瘤] R737.33[医药卫生—临床医学]