家族性非综合征型先天缺牙2例  

Non-syndromic familial congenital dental deficiency:two cases report

作　　者：陈雪 黎远皋[1] Chen Xue;Li Yuangao(Dept.of Stomatology,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院口腔科,北京100191

出　　处：《华西口腔医学杂志》2022年第4期483-488,共6页West China Journal of Stomatology

摘　　要：先天缺牙可导致美观和咀嚼功能异常,对患者的生活质量有很大影响。基因遗传是先天缺牙的决定因素,可遵循常染色体显性、隐性或X染色体连锁遗传模式,但具体机制并不明确。先天缺牙的患病率不高,家族性非综合征型先天缺牙更为罕见。本文报道了2例家族性非综合征型先天缺牙,并对先天缺牙的病因机制、临床表现和治疗方案等进行文献回顾。Congenital dental deficiency can lead to aesthetic and masticatory dysfunction,which have a great effect on the quality of life of patients.Genetic inheritance is the determining factor of congenital dental deficiency,which may follow the pattern of autosomal dominant,recessive,or sex chromosome inheritance.However,the specific genetic mechanisms are not clear.The prevalence of congenital absence of permanent teeth in the general population worldwide are not high,and familial oligodontia in clinically healthy patients is rare.This paper reported two cases of familial non-syndromic congenital teeth loss and included a review of literature referring to the etiology,clinical manifestations,and treatment of congenital dental deficiency.

关 键 词：先天牙缺失 非综合征型 病因 

分 类 号：R78[医药卫生—口腔医学]