Brain-derived neurotrophic factor in main neurodegenerative diseases  

作　　者：Serena Camuso Sonia Canterini 

机构地区：[1]Division of Neuroscience,Department of Psychology,University La Sapienza,Rome,Italy [2]PhD Program in Behavioral Neuroscience,Sapienza University of Rome,Rome,Italy

出　　处：《Neural Regeneration Research》2023年第3期554-555,共2页中国神经再生研究（英文版）

基　　金：supported by“Sapienza”University(Ateneo2021_RP12117A8857C5F8 to SC)。

摘　　要：Discovered in pig brains in 1982,the brain-derived neurotrophic factor(BDNF)is one of the most studied and characterized neurotrophins in the central nervous system.In recent years,BDNF has received considerable attention for its importance in the development and maintenance of normal brain function.This is because BDNF plays an important role in crucial functions of the nervous system,such as the survival,differentiation,and maturation of neurons and glial cells as well as the actions of neuroprotection in adverse conditions,such as glutamatergic overstimulation,cerebral ischemia,hypoglycemia,and neurotoxicity(Kowiański et al.,2018).

关 键 词：STIMULATION DISEASES 

分 类 号：R741[医药卫生—神经病学与精神病学]