Apigenin as a promising myocyte protectant against damage and degradation  

作　　者：XIAO HUANG ZHIHAI YU LIJUAN NING YU LEI XUEFEI ZHANG ZHUYING WANG 

机构地区：[1]Institute of Cultural and Technological Industry Innovation of Tongren,Tongren,554300,China [2]School of Sports and Physical Education,Nanjing Normal University,Nanjing,210046,China [3]School of Physical Education,Guangxi University of Science and Technology,Liuzhou,545006,China [4]Department of Urology Surgery,Chongqing University Three Gorges Hospital,Chongqing,404000,China [5]School of Sports and Health Science,Tongren University,Tongren,554300,China

出　　处：《BIOCELL》2022年第2期383-388,共6页生物细胞（英文）

基　　金：supported by the China Postdoctoral Science Foundation(Grant No.2019M653494);Special Field Projects of Guizhou Education Committee(Grant No.KY2019072);High-level Innovative Talents in Guizhou Province(Grant No.2018-2016-023).

摘　　要：Myocytes power the movement of all organs in the body.Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases.Apigenin,a kind of flavone,is being used to treat many disorders.It exerts a host of different pharmacological activities,such as anti-inflammatory,anti-mutagenic,cardioprotective,and antioxidant effects.Accordingly,apigenin is considered a promising candidate for myocyte protection.In this review,we introduced the characteristics of apigenin.The means of apigenin protection of myocytes as well as the mechanism were summarized and discussed.The protective effects can be classified into proliferation-promoting,anti-inflammatory,atrophy-preventing,metabolism-increasing,and antioxidative effects.Additionally,we provided some outlook on the valuable applications of apigenin in sports medicine,which eagerly require further fundamental research.

关 键 词：APIGENIN MYOCYTE Protectant Pharmacological activity 

分 类 号：O62[理学—有机化学]