supported by grants from the National Natural Science Foundation of China(31971045,32171103)。
More and more studies have suggested an essential role of sarcoplasmic reticulum(SR)Ca^(2+)leak of atrial myocytes in atrial diseases such as atrial fibrillation(AF).The increasing interest in atrial Ca^(2+)signaling ...
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Science(XDA16020400 to P.H.);Ministry of Science and Technology of China(2017YFA0102700 to P.H.);the National Natural Science Foundation of China(32170804 to P.H.and 81200355 to W.Y.);CAS-Youth Innovation Program Association(2016246 to W.Y.);Shanghai Natural Science Foundation(18ZR1446300 to W.Y.).
Long non-coding(lnc)RNA plays important roles in many cellular processes.The function of the vast majority of lncRNAs remains unknown.Here we identified that lncRNA-1700113A16RIK existed in skeletal muscle stem cells(...
Supported by the Higher Education Commission(HEC),Pakistan Scholarship for Ph.D.Studies to Razzaq SS,No.520-148390-2BS6-011.
BACKGROUND Heart diseases are the primary cause of death all over the world.Following myocardial infarction,billions of cells die,resulting in a huge loss of cardiac function.Stem cell-based therapies have appeared as...
Objective: Exposure of the heart to repeated, brief episodes of coronary occlusion/reperfusion prevents lethal myocyte injury. Necrosis and apoptosis, two seemingly distinct mechanisms of cell death caused by ischemia...
the“111”Project;the financial support by China Agriculture Research System of MOF and MARA.
To define the relationship between dietary nutrient density, calcium (Ca), and meat quality in meatducks. A total of 288 male Cherry Valley SM3 medium ducklings were fed a common standard starter dietuntil d 14. At 15...
This work was supported by grants from the National Key Research and Development Program of China(2016YFA0502201)awarded to Prof.Huazhang An;the National Natural Science Foundation of China(Nos.U1801283,31870908);the Guangdong Provincial Science and Technology Program(No.2019B030301009);the SZU Top Ranking Project(No.86000000210)awarded to Prof.Weilin Chen;the National Natural Science Foundation of China(No.81771711)awarded to Prof.Wengang Song;the Guangdong Provincial Science and Technology Program(No.2019A1515110086)awarded to Xibao Zhao.We thank Jessica Kate Tamanini(Scientific Editor,Shenzhen University School of Medicine)for editing the manuscript.
The polarization of macrophages to the M1 or M2 phenotype has a pivotal role in inflammation and host defense;however,the underlying molecular mechanism remains unclear.Here,we show that myocyte enhancer factor 2 C(ME...
supported by the China Postdoctoral Science Foundation(Grant No.2019M653494);Special Field Projects of Guizhou Education Committee(Grant No.KY2019072);High-level Innovative Talents in Guizhou Province(Grant No.2018-2016-023).
Myocytes power the movement of all organs in the body.Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases.Apigenin,a kind of flavone,is being used to treat many disorders....
This work was supported by grants from the National Natural Science Foundation of China(No.81860207);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT13058);the Guizhou Science and Technology Foundation(Nos.[2019]1437 and[2017]1149);the Department of Education of Guizhou Province(No.KY[2021]313 and YJSCXJH(2020)145).
Myocyte enhancer factor 2C(MEF2C)is highly expressed in the nervous system,and regulates neuro-development,synaptic plasticity,and inflammation.However,its mechanism in Alzheimer’s disease(AD)is underestimated.In thi...
Objective:Cardiac hypertrophy is an adaptive reaction of the heart against cardiac overloading,but continuous cardiac hypertrophy can lead to cardiac remodeling and heart failure.Cardiac hypertrophy is mostly consider...
At some point after birth,myocyte hyperplasia ceases,and myocyte hypertrophy accounts for the remaining growth of myocytes composing the heart from that point forward.Heart weight increases in proportion to myocyte vo...