Exclusion and Co-expression of Aversive Olfactory Long-Term Memories in Drosophila  

作　　者：Bohan Zhao Xuchen Zhang Janjan Zhao Qian Li 

机构地区：[1]School of Life Sciences,IDG/MeGovern Institute for Brain Research,Tsinghua University,Beijing 100084,China [2]Tsinghua-Peking Center for Life Sciences,Bejing 100084,China [3]Present Address:Centre for Neural Circuits and Behaviour,University of Oxford,Oxford OX13SR,UK [4]Present Addrss:Department of Molecular and Cellular,Physiology and Howard Hughes Medical Institute,Stanford University School of Medicine,Stanford,CA 94305,USA

出　　处：《Neuroscience Bulletin》2022年第6期657-660,共4页神经科学通报（英文版）

基　　金：supported by granes from the National Science Foundation of China(31970955)and the Tsinghua-Peking Center for Life Sciences.

摘　　要：Long-term memory(LTM)allows animals to use remote past experiences to guide current and future decisions.One of the widely-used animal models for LTM research is the fruit-fly Drosophila melanogaster,which can form different types of LTM after different learning paradigms[1-6].Spaced training-induced LTM(spLTM),perhaps the most studied Drosophila LTM,requires multiple repeated learning trials with a 15-min resting interval between each trial.For decades,spLTM has been considered the only aversive olfactory LTM that can last for>7 days[1].Recently,two other types of LTM,context-dependent LTM(cLTM)[5]and merged LTM(mLTM)[6],have been discovered with the same long duration as spLTM,and can be formed with only one aversive learning trial.

关 键 词：DROSOPHILA OLFACTORY MELANOGASTER 

分 类 号：R74[医药卫生—神经病学与精神病学]