2016-2020年山东省食用植物油中氯丙醇酯污染水平及人群暴露评估  

Contamination level and population exposure assessment of chloropropanol esters in edible vegetable oil in Shandong Province from 2016 to 2020

作　　者：朱丽君[1] 王立友[1] 王楷 王雪婷 张静[1] 杨路平[2] Zhu Lijun;Wang Liyou;Wang Kai;Wang Xueting;Zhang Jing;Yang Luping(Dezhou Center for Disease Control and Prevention,Dezhou 253014,China;Shandong Center for Disease Control and Prevention,Jinan 250014,China)

机构地区：[1]德州市疾病预防控制中心,德州253014 [2]山东省疾病预防控制中心,济南250014

出　　处：《卫生研究》2022年第5期823-828,共6页Journal of Hygiene Research

基　　金：山东省中医药科技项目(No.2021M222)。

摘　　要：目的了解山东省市售食用植物油中2-氯丙醇酯和3-氯丙醇酯的污染水平,并对山东省普通人群通过植物油摄入3-氯丙醇酯的暴露量进行风险评估。方法2016—2020年采集山东省16个地级市商店和农贸市场406份独立包装食用植物油。按照《2016年国家食品污染和有害因素风险监测手册》,采用气相色谱-三重四极杆串联质谱检测,同位素内标法定量,测定植物油中2-氯丙醇酯和3-氯丙醇酯含量。结合人群体重、油脂消费量采用点评估方法对山东省居民3-氯丙醇酯的暴露情况进行评估。结果3-氯丙醇酯检出率为92.4%(375/406),浓度范围为<检出限(limit of detection,LOD)-18.4mg/kg,中位值为0.470mg/kg,平均值为0.833mg/kg,最大值出现在稻米油;2-氯丙醇酯检出率为88.7%(360/406),浓度范围为<LOD-8.46mg/kg,中位值为0.204mg/kg,平均值为0.432mg/kg,最大值出现在稻米油。各年龄组人群平均暴露量均小于每日耐受摄入量,儿童组(2-6岁)和青少年组(7-10岁)高端暴露量大于每日耐受摄入量。结论2016-2020年山东省市售食用植物油氯丙醇酯污染普遍存在,检测高值出现在稻米油中,高风险情况下儿童组(2-6岁)和青少年组(7-10岁)通过植物油摄入3-氯丙醇酯存在健康风险。OBJECTIVETo investigate the contamination of 2-chloropropanol esters and 3-chloropropanol esters in commercial edible vegetable oils in Shandong Province,and to assess the dietary 3-chloropropanol esters exposure and the health risk of intaking 3-chloropropanol esters.METHODSFrom 2016 to 2020,406 individually packaged edible vegetable oils were collected from stores and farmers'markets in 16 prefecture-level cities in Shandong Province.According to the 2016 National Food Contamination and Harmful Factors Risk Monitoring Manual,using gas chromatographytriple quadrupole tandem mass spectrometry detection,isotope internal standard method for quantification,laboratory determination of 2-chloropropanol ester and 3-chloropropanol in vegetable oil ester content.Combined with population weight,oil consumption and monitoring data,the point assessment method was used to evaluate the exposure of residents in Shandong Province to 3-chloropropanol esters.RESULTSThe detection rate of 3-chloropropanol ester was 92.4%(375/406),the concentration range was<limit of detection(LOD)-18.4 mg/kg,the median was 0.470 mg/kg,the average was 0.833 mg/kg,and the maximum value was 18.4 mg/kg in rice oil;the detection rate of 2-chloropropanol ester was 88.7%(360/406),the concentration range was<LOD-8.46 mg/kg,the median value was 0.204 mg/kg,the average value was 0.432 mg/kg,and the maximum value was 8.46 mg/kg in rice oil.The average exposure of each age group was less than the tolerable daily intake,and the high-end exposure of the children(2-6 years old)and adolescents(7-10 years old)group was greater than the tolerable daily intake.CONCLUSIONThe contamination of chloropropanol esters of edible vegetable oil in Shandong Province from 2016 to2020 is widespread,and the highest detection value appears in rice oil.Children(2-6 years old)and adolescents(7-10 years old)in highrisk situations ingest 3-chloropropanol esters present health risks.

关 键 词：2-氯丙醇酯 3-氯丙醇酯 食用植物油 暴露评估 

分 类 号：R155.51[医药卫生—营养与食品卫生学] TS201.6[医药卫生—公共卫生与预防医学]