眼部迷芽瘤的研究进展  

Research progress of ocular choristoma

作　　者：罗叶芳 马瑞欣 王钰娇[1] 何为民[1] Luo Yefang;Ma Ruixin;Wang Yujiao;He Weimin(Department of Ophthalmology,West China Hospital of Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院眼科,成都610041

出　　处：《中国医师杂志》2022年第9期1428-1432,共5页Journal of Chinese Physician

基　　金：四川省科技计划项目(2021YFS0212);四川大学华西医院临床研究孵化项目(2018HXFH024)。

摘　　要：眼部迷芽瘤是由异位生长的一些正常结构的组织构成,发病机制尚未明确,组织病理学显示为夹杂着表皮附件、平滑肌细胞、成熟脂肪组织、泪腺、淋巴结、骨骼肌纤维、软骨和骨等致密结缔组织。因其临床罕见,现有文献大部分为个案报道,临床表现常缺乏特异性,需与其他眼部肿物鉴别,是否手术切除取决于眼部症状、对外观的影响和临床确诊的需要。本文对眼部迷芽瘤的流行病学、病因及发病机制、临床表现、诊断与鉴别诊断以及治疗方面的研究进展进行综述。Ocular choristoma is composed of ectopic tissues with normal structures.The pathogenesis still remains uncertain.Histopathologically,it is a dense connective tissue mixed with epidermal appendages,smooth muscle cells,mature adipose tissue,lacrimal glands,lymph nodes,skeletal muscle fibers,cartilage and bone.Because of its low incidence,most of published literature are case reports.The clinical manifestations are non-specific and we need to distinguish it from other ocular masses.The choice of surgical resection depends on the ocular symptoms,the effect on appearance,and the need for clinical confirmation.This paper reviews the epidemiology,etiology,pathogenesis,clinical manifestations,diagnosis,differential diagnosis and treatment of ocular choristoma.

关 键 词：迷芽瘤 眼肿瘤 GOLDENHAR综合征 表皮痣综合征 

分 类 号：R739.7[医药卫生—肿瘤]