纸基微流控芯片的印刷制造工艺及其在食品安全检测中的应用  

Printing and Manufacturing Technology of Microfluidic Paper-based Analytical Devices and Its Application in Food Safety Detection

作　　者：李琼阳 陈心雨 徐小虎 万小芳 田君飞 LI Qiong-yang;CHEN Xin-yu;XU Xiao-hu;WAN Xiao-fang;TIAN Jun-fei(State Key Laboratory of Pulp and Paper Engineering,School of Light Industry and Engineering,Guangzhou 510641,China;Experimental Teaching Demonstration Center of Light Industry and Food Science,South China University of Technology,Guangzhou 510641,China)

机构地区：[1]华南理工大学轻工科学与工程学院制浆造纸工程国家重点实验室,广州510641 [2]华南理工大学轻工与食品国家级实验教学示范中心,广州510641

出　　处：《包装工程》2022年第19期27-39,共13页Packaging Engineering

基　　金：国家自然科学基金(82072016);广东省基础与应用基础研究基金(2021A1515011511);华南理工大学国家大学生创新创业训练计划资助项目(202210561106)。

摘　　要：目的探究纸基微流控芯片的发展现状,为纸基微流控芯片进一步研发和推广应用提供借鉴和参考。方法通过调研文献,根据检测原理及印刷制备工艺对纸基微流控芯片进行阐述,然后对微流控芯片在食品安全检测中的应用研究进展进行总结。结果纸基微流控芯片适用于比色法、荧光法、电化学法及表面增强拉曼光谱等多种检测方法,印刷制备工艺也呈现多样化发展趋势。纸基微流控芯片检测技术成功应用于食品添加剂、污染物、成分分析及智能食品包装等安全检测领域。结论纸基微流控芯片应用潜力巨大,仍需进一步优化技术工艺以克服制约其发展的潜在瓶颈问题。The work aims to explore the development status of microfluidic paper-based analytical devices(μPADs),to provide reference for further development and application ofμPADs.TheμPADs were introduced according to the de-tection principle and fabrication techniques through study of literature.Furthermore,the application research progress ofμPADs in food safety detection was summarized.TheμPADs were applicable to colorimetric method,fluorescence me-thod,electrochemical method and surface enhanced Raman spectroscopy,etc.The fabrication techniques also presented a diversified development trend.TheμPADs detection technology has been successfully applied to the safety detection of food additives,pollutants,composition analysis and intelligent food packaging.TheμPADs have huge application poten-tial but it is still necessary to further optimize the technical process to overcome the potential bottlenecks restricting its development.

关 键 词：纸基微流控芯片 制备工艺 印刷 食品安全检测 

分 类 号：TS805[轻工技术与工程]