四种杀虫剂对白纹伊蚊(Aedes albopictus)细胞株(C6/36)的细胞遗传学效应  

CYTOGENETIC EFFECTS OF 4 PESTICIDES ON THE MOSQUITO(Aedes albopictus)CELL LINE(C6/36)

作　　者：张锡然[1] 王建华[1] 陈玉泽[1] 施立明[1] Zhang Xiran;Wang Jianhua;Chen Yuze;Shi Liming(Kunming Institute of zoology,Acodemia Sinico,Kunming)

机构地区：[1]中国科学院昆明动物研究所,昆明

出　　处：《Zoological Research》1985年第1期95-100,I0005,共7页动物学研究（英文）

摘　　要：本文研究了四种杀虫剂:敌敌畏乳剂,灭害灵,甲基对硫磷,叶蝉散对白纹伊蚊细胞株(C6/36)染色体畸变和姐妹染色单体互换(SCE)的影响。结果表明:0.1%和0.01%浓度的敌敌畏,可使(SCE)频率明显增加,而染色体畸变率只在0.1%浓度有显著增加;0.5%的灭害灵,可使SCE频率明显增加,而染色体畸变增加不明显;甲基对硫磷和叶蝉散的实验结果表明,无论是染色体畸变和SCE频率均没有明显增加。The four pesticides,milk of 80%dichlorvos,resmethrin,parathipnmethyl and mipcin,were tested for their abilities to induce chromosomal aberrations and sister-chromatid exchange frequencies in mosquito cell line(C6/36).The results show that the effectivities of these pesticides were strikingly different.(1)The significant increase of SCE frequencies occurred under the doses of 0.1%and 0.01%milk of dichlovos,but the chromosomal aberrations were found significantly only when the dose of 0.1%was treated.(2)The increasing frequencies of SCE induced with the dose of 0.5%resmethrin was significant,but the chromosomal aberration did not differ significantly from the control.When the dose of 0.1%resmethrin was used,neither frequencies of SCE or chromosomal aberrations were enhanced.(3)From our results we find no evidence that parathionmethyl and mipcin are mutagenic in enhancing frequencies of SCE and chromosomal aberrations.In addition,the different inductive capacities of the four pesticides and possible reasons for those were also discussed.

关 键 词：细胞遗传 杀虫剂 蚊 细胞株 

分 类 号：R73[医药卫生—肿瘤]