Non-medicalization of medical science:Rationalization for future  

作　　者：Madhukar Mittal Parth Jethwani Dukhabandhu Naik MK Garg 

机构地区：[1]Department of Endocrinology and Metabolism,All India Institute of Medical Sciences Jodhpur,Jodhpur 342005,India [2]Department of Endocrinology and Metabolism,Jawaharlal Institute of Postgraduate Medical Education and Research,Puducherry 605006,India

出　　处：《World Journal of Methodology》2022年第5期402-413,共12页世界方法学杂志

摘　　要：As we delve into the intricacies of human disease,millions of people continue to be diagnosed as having what are labelled as pre-conditions or sub-clinical entities and may receive treatments designed to prevent further progression to clinical disease,but with debatable impact and consequences.Endocrinology is no different,with almost every organ system and associated diseases having subclinical entities.Although the expansion of these“grey”pre-conditions and their treatments come with a better understanding of pathophysiologic processes,they also entail financial costs and drug adverse-effects,and lack true prevention,thus refuting the very foundation of Medicine laid by Hippocrates“Primum non nocere”(Latin),i.e.,do no harm.Subclinical hypothyroidism,prediabetes,osteopenia,and minimal autonomous cortisol excess are some of the endocrine preclinical conditions which do not require active pharmacological management in the vast majority.In fact,progression to clinical disease is seen in only a small minority with reversal to normality in most.Giving drugs also does not lead to true prevention by changing the course of future disease.The goal of the medical fraternity thus as a whole should be to bring this large chunk of humanity out of the hospitals towards leading a healthy lifestyle and away from the label of a medical disease condition.

关 键 词：PREDIABETES Subclinical hypothyroidism OSTEOPENIA Mild autonomous cortisol secretion PRE-CLINICAL MEDICALIZATION 

分 类 号：R73[医药卫生—肿瘤]