Nonalcoholic steatohepatitis and hepatocellular carcinoma: Beyond the boundaries of the liver  

作　　者：Tarana Gupta 

机构地区：[1]Department of Medicine,Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences,Rohtak 124001,Haryana,India

出　　处：《World Journal of Gastroenterology》2022年第36期5380-5382,共3页世界胃肠病学杂志（英文版）

摘　　要：The burden of non-alcoholic steatohepatitis (NASH) related hepatocellularcarcinoma (HCC) is drawing attention due to the emerging epidemic of obesityand metabolic syndrome and is expected to increase in the near future.Antidiabetic medications, air pollutants, and newer genetic mutations are latestconcerns as risk factors for HCC development in patients with NASH. Althoughmolecular signatures are very accurate, they are not cost-effective and cannot beapplied in larger population due to logistic issues. We need multicentric longitudinalstudies including diverse geographical areas to evaluate the complexinterplay of different risk factors and genetics in these patients.

关 键 词：Non-alcoholic steatohepatitis Hepatocellular carcinoma CIRRHOSIS Genetic factors Lifestyle factors SURVEILLANCE 

分 类 号：R575[医药卫生—消化系统] R735.7[医药卫生—内科学]