Treatment for giant congenital nevi moves a step closer  

作　　者：Joanna Pozniak Jean-Christophe Marine 

机构地区：[1]Laboratory for Molecular Cancer Biology,VIB Center for Cancer Biology,VIB,Leuven,Belgium [2]Oncology Department,KU Leuven,Leuven,Belgium

出　　处：《Cell Research》2022年第9期799-800,共2页细胞研究（英文版）

摘　　要：Giant congenital melanocytic nevus,defined as a pigmented melanocytic lesion present at birth that will reach a diameter of≥20 cm in adulthood,is associated with severe complica-tions including malignant transformation into cutaneous melanoma,affects the central nervous system(neurocuta-neous melanosis),and has major psychosocial impact due to its unsightly appearance.In a study recently published in Cell,Choi et al.used three mouse preclinical models to search for new non-invasive treatments,describing a promising strategy that promotes the clearing of these pigmented lesions by the innate immune system.

关 键 词：CONGENITAL MELANOMA CLOSER 

分 类 号：R739.5[医药卫生—肿瘤]