岩藻聚糖硫酸酯的研究进展  

Research progress of fucoidan

作　　者：柯悦 孙闫小凡 董鸿春 魏团团 任丹丹 汪秋宽 KE Yue;SUN Yan-Xiao-Fan;DONG Hong-Chun;WEI Tuan-Tuan;REN Dan-Dan;WANG Qiu-Kuan(College of Food Science and Engineering,Dalian Ocean University,Dalian 116023,China;Key Laboratory of Aquatic Product Processing and Utilization of Liaoning Province,Dalian 116023,China;Nation Research and Development Branch Center for Seaweed Processing,Dalian 116023,China;Collaborative Innovation Center of Seafood Deep Processing,Dalian Polytechnic University,Dalian 116023,China)

机构地区：[1]大连海洋大学食品科学与工程学院,大连116023 [2]辽宁省水产品加工及综合利用重点实验室,大连116023 [3]国家海藻加工技术研发分中心,大连116023 [4]大连工业大学,海洋食品精深加工关键技术省部共建协同创新中心,大连116023

出　　处：《食品安全质量检测学报》2022年第18期6057-6065,共9页Journal of Food Safety and Quality

基　　金：国家重点研发计划项目(2018YFD0901104);辽宁省教育厅科学研究项目(JL201909);财政部和农业农村部:国家现代农业产业技术体系资助项目(CARS-50)。

摘　　要：岩藻聚糖硫酸酯为含有硫酸基团的水溶性杂多糖,结构复杂,具有很多生物活性,包括抗氧化、降血脂、降血糖、抗炎、抗凝血、抗病毒、免疫调节等,使其在功能性食品、健康食品等领域有广阔的应用前景,在医药领域也有很大的应用潜力。不同的原料及其提取分离纯化的方法对其结构均有一定的影响,进而影响到其生物活性。且由于其结构的复杂性,对岩藻聚糖硫酸酯结构的解析方法也成为了研究重点。本文对岩藻聚糖硫酸酯的提取、分离纯化、结构分析及生物活性的研究进展进行了综述,并对岩藻聚糖硫酸酯在健康领域的应用现状进行了分析,以期为岩藻聚糖硫酸酯的研究与应用提供参考。Fucoidan is water-soluble heteropolysaccharide containing sulfuric groups,with a complex structure and many biological activities,including anti-oxidation,lowering blood lipids,lowering blood sugar,anti-inflammatory,anti-coagulation,anti-virus,immune regulation,etc.It has broad application prospects in functional food,health food and other fields,and also has great application potential in the field of medicine.Different raw materials as well as its extraction,separation and purification methods have a certain influence on their structure,which will affect the biological activity of fucoidan.The analysis method of fucoidan structure is also the focus of research,because of the complexity of its structure.This paper reviewed the research progress of the extraction,separation and purification,structure analyses and biological activities of fucoidan,and also analyzed the application status of fucoidan in the field of health,in order to provide a reference for the research and application of fucoidan.

关 键 词：岩藻聚糖硫酸酯 提取 分离 结构 生物活性 

分 类 号：TS201.2[轻工技术与工程—食品科学]