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作 者:李柳 穆迎春[2,3] 刘璐 张洪玉 徐锦华[2,3] 杨臻 乔璐 宋金龙 LI Liu;MU Ying-chun;LIU Lu;ZHANG Hong-yu;XU Jin-hua;YANG Zhen;QIAO Lu;SONG Jin-long(College of Food Science and Technology,Shanghai Ocean University,Shanghai 200120;Chinese Academy of Fishery Sciences,Beijing 100141;Key Laboratory of Control of Quality and Safety for Aquatic Products,Ministry of Agriculture and Rural Affairs,Beijing 100141)
机构地区:[1]上海海洋大学食品学院,上海200120 [2]中国水产科学研究院,北京100141 [3]农业农村部水产品质量安全控制重点实验室,北京100141
出 处:《生物技术通报》2022年第9期84-95,共12页Biotechnology Bulletin
基 金:中央级公益性科研院所基本科研业务费(2021A003);农业农村部淡水渔业健康养殖重点实验室开放课题(ZJK202101);财政部和农业农村部:国家现代农业产业技术体系资助(CARS-48)。
摘 要:氟喹诺酮类抗生素属于喹诺酮类抗生素,是一类人畜通用的抗生素。近年来,被广泛应用于人类和畜牧、水产等养殖业领域,然而其大量使用,造成在环境中的不断残留和累积,给自然环境和人类健康造成了较大威胁。现有研究表明,微生物降解是有效去除氟喹诺酮类抗生素残留污染的有效方法之一。本文总结和介绍了近年来氟喹诺酮类抗生素微生物降解单株菌和混合菌群、微生物降解酶、降解途径以及微生物降解氟喹诺酮类抗生素的实际应用,并对目前氟喹诺酮类抗生素微生物降解研究中存在的问题进行了分析,以及对未来氟喹诺酮类抗生素微生物降解研究的重点进行了探讨,以期为后续的研究提供参考。Fluoroquinolone antibiotics belong to quinolone antibiotics,is a kind of common antibiotics for human and livestock.In recent years,it has been widely used in human and animal husbandry,aquaculture and other aquaculture fields.However,its massive use has caused continuous residue and accumulation in the environment,posing a great threat to the natural environment and human health.Existing studies show that microbial degradation is one of the effective methods to remove the residual contamination of fluoroquinolone antibiotics.This paper summarized and introduced the practical application of fluoroquinolone antibiotics in microbial degradation of single strain and mixed bacteria,microbial degradation enzymes,degradation pathways and fluoroquinolone antibiotics in recent years,and analyzed the existing issues in the study of fluoroquinolone antibiotics microbial degradation.In addition,the paper also discussed the research focus of fluoroquinolone antibiotics microbial degradation in the future,aiming to provide reference for the follow-up research.
分 类 号:X50[环境科学与工程—环境工程] X172
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