Primary squamous cell carcinoma with sarcomatoid differentiation of the kidney associated with ureteral stone obstruction: A case report  

作　　者：Xue-Hua Liu Qian-Ming Zou Jia-Dong Cao Zhi-Chao Wang 

机构地区：[1]Department of Urology Surgery,Fangcun Hospital of Guangdong Provincial Hospital of traditional Chinese Medicine,Guangzhou 510120,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2022年第32期11942-11948,共7页世界临床病例杂志

摘　　要：BACKGROUND Primary squamous cell carcinoma(SCC)with sarcomatoid differentiation of the kidney was rarely reported.This disease is usually related to renal stones,and due to a lack of symptoms and radiological features,patients usually attend the hospital with late stage disease.CASE SUMMARY A 54-years-old female presented with left flank pain and an abdominal mass for 6 mo.Imaging studies revealed that the left kidney was enlarged and massive hydronephrosis was present.A stone was seen in the ureteropelvic junction.The patient subsequently underwent left radical nephrectomy,and histopathological examination of the mass revealed a poorly differentiated renal SCC with sarcomatoid differentiation.After primary surgery,the patient received four cycles of tirelizumab.Four months later,the patient developed adrenal,lymph,and uterine appendage metastases.CONCLUSION SCC of the kidney has a poor prognosis,and should be considered in patients with a renal mass,long-standing urinary calculi and massive hydronephrosis.

关 键 词：Squamous cell carcinoma Sarcomatoid differentiation KIDNEY Ureteral stone Case report 

分 类 号：R737.11[医药卫生—肿瘤] R693.2[医药卫生—临床医学]