Neural circuits underlying motor and non-motor defects of Parkinson’s disease  

作　　者：Minqing Jiang 

机构地区：[1]McGovern Institute for Brain Research,Department of Brain and Cognitive Sciences,Massachusetts Institute of Technology,Cambridge,MA 02169,USA

出　　处：《The Innovation》2022年第6期9-10,共2页创新（英文）

摘　　要：AN OVERVIEW OF PARKINSON’S DISEASE Parkinson’s disease(PD)is a neurodegenerative disorder that causes unintended and uncontrollable movements,such as tremors,rigidity,and difficulty with balance and coordination.Neuronal degeneration in the basal ganglia network has been suggested as a likely cause for some PD symptoms.More specifically,such degeneration would lead to an imbalance between the direct pathway(from striatum to substantia nigra)and the indirect pathway(from striatum to pallidum),which subsequently drives movement deficits.1 Current treatments for the motor dysfunction of PD include dopamine agonists,deep brain stimulation(DBS),and physical therapy.

关 键 词：DEGENERATION STIMULATION PARK 

分 类 号：R742.5[医药卫生—神经病学与精神病学]