发酵大豆蛋白肽增强小鼠机体免疫力及抗疲劳能力  

Fermented soybean protein peptide enhances immunity and anti-fatigue ability of mice

作　　者：方磊 张瑞雪 魏颖 FANG Lei;ZHANG Rui-xue;WEI Ying(Beijing Engineering Research Center of Protein&Functional Peptides,China National Research Institute of Food and Fermentation Industries,Beijing 100015,China)

机构地区：[1]中国食品发酵工业研究院有限公司,北京市蛋白功能肽工程技术研究中心,北京100015

出　　处：《粮食与油脂》2022年第12期146-150,共5页Cereals & Oils

基　　金：十三五国家重点研发计划(2016YFD0400604)。

摘　　要：为研究发酵大豆蛋白肽对小鼠机体免疫力及抗疲劳能力的影响,对小鼠脾淋巴细胞、T/B淋巴细胞增殖、血清溶血素、NK细胞杀伤力、运动能力及相关血清指标进行了测定。结果表明:发酵大豆蛋白肽能显著提高小鼠脾淋巴细胞和T/B淋巴细胞的增殖能力,显著提高血清溶血素水平和NK细胞杀伤力;负重游泳试验发现服用了发酵大豆蛋白肽的小鼠负重游泳时间长于空白组(P<0.05),发酵大豆蛋白肽组小鼠血液中尿素氮(BUN)的含量和乳酸脱氢酶(LDH)活力均降低(P<0.05)。适量摄入发酵大豆蛋白肽具有增强机体免疫力及抗疲劳的作用。In order to study the effects of fermented soybean protein peptides on the immunity and antifatigue ability of mice,spleen lymphocytes,T/B lymphocyte proliferation,serum hemolysin,NK cell killing ability,exercise ability and related serum indexes were carried out.The results showed that fermented soybean protein peptide could significantly increase the proliferation ability of mouse spleen lymphocytes and T/B lymphocytes,and significantly increase the serum hemolysin level and NK cell lethality.The weight-bearing swimming experiment found that the weight-bearing swimming time of the mice in the fermented soybean protein peptide group was longer than that of the blank group(P<0.05).The blood urea nitrogen content and lactate dehydrogenase activity of the fermented soybean protein peptide group decreased(P<0.05).Appropriate intake of fermented soybean protein peptides has the effect of enhancing immunity and anti-fatigue.

关 键 词：发酵大豆蛋白肽 T/B淋巴细胞 血清溶血素 抗疲劳 

分 类 号：TS201.2[轻工技术与工程—食品科学]