Uterine large cell neuroendocrine carcinoma with unusual colonic metastasis  

作　　者：Antonio Ieni Giuseppe Angelico Rosalba De Sarro Francesco Fleres Antonio Macrì Giovanni Tuccari 

机构地区：[1]Department of Human Pathology of Adult and Evolutive Age“Gaetano Barresi”,Section of Anatomic Pathology,University of Messina,98125 Messina,Italy [2]Student in Medicine and Surgery,University of Messina,98125 Messina,Italy [3]Department of Human Pathology of Adult and Evolutive Age“Gaetano Barresi”,Section of General Surgery,University of Messina,Azienda Ospedaliera Universitaria“Policlinico Gaetano Martino”,98125 Messina,Italy.

出　　处：《Journal of Cancer Metastasis and Treatment》2017年第1期144-149,共6页癌症转移与治疗（英文版）

摘　　要：A 78-year-old female patient arrived at our practice complaining of progressive abdominal increase and presenting a clinical picture of intestinal obstruction.At physical examination,the abdomen appeared distended,moderately painful with the presence of a mass of hard consistency.Abdominal computed tomography scan showed a large hypodense pelvic mass that indicated a compression and lateral deviation of the uterus and bladder.Microscopically,the mass showed a uniform solid pattern,composed of medium and large-sized cells with hyperchromatic and pleomorphic nuclei demonstrating high mitotic activity and diffuse immunoreactivity for estrogen receptors and synaptophysin.A diagnosis of uterine poorly differentiated large cell neuroendocrine carcinoma,arising in the endometrium with an unusual colonic metastatic localization,was made.

关 键 词：Neuroendocrine carcinoma METASTASIS UTERUS differential diagnosis immunohistochemistry 

分 类 号：R73[医药卫生—肿瘤]