戊糖片球菌治疗婴儿肠绞痛的临床研究概述  

Summary of clinical research of Pediococcus pentosaceus in treatment of infantile colic

作　　者：吴诗寅 蔡美琴[1] WU Shiyin;CAI Meiqin(Shanghai Jiao Tong University School of Public Health,Shanghai 200025,China)

机构地区：[1]上海交通大学公共卫生学院,上海200025

出　　处：《上海交通大学学报（医学版）》2022年第11期1633-1637,共5页Journal of Shanghai Jiao tong University:Medical Science

摘　　要：婴儿肠绞痛是一种常见病,其病因尚未明确,可能与肠道菌群失调有关。戊糖片球菌是乳酸菌科片球菌属的益生菌,具有增强宿主免疫力、改善肠道菌群多样性等作用。该文对戊糖片球菌的抑菌能力、肠道定植能力和抗生素敏感性等益生菌特性及其抗氧化、抗病毒和免疫调节等益生功能进行介绍,并阐述婴儿肠绞痛的可能发病机制、戊糖片球菌治疗婴儿肠绞痛的功效和潜在作用机制,以及国内外临床研究现状,以期为戊糖片球菌治疗婴儿肠绞痛提供科学依据。Infantile colic is a common disease. Its etiology is not clear, which may be related to the imbalance of intestinal flora.Pediococcus pentosaceus is a probiotic of Pediococcus of Lactobacillaceae. It can enhance host immunity and improve the diversity of intestinal flora. This paper will introduce the characteristics of probiotics such as antibacterial capability, intestinal colonization ability and antibiotic sensitivity of Pediococcus pentosaceus, and the probiotic functions such as antioxidant, antiviral and immune regulation, and elaborate on the possible pathogenesis of infantile colic, the efficacy and potential mechanism of Pediococcus pentosaceus in the treatment of infantile colic, and the current situation of clinical research at home and abroad, in order to provide a scientific basis for Pediococcus pentosaceus in the treatment of infantile colic.

关 键 词：戊糖片球菌 婴儿肠绞痛 益生特性 

分 类 号：R722.19[医药卫生—儿科]