2016—2018年北京市学龄儿童维生素D营养状况及其分布特点  

Vitamin D status and distribution in Beijing school aged children in 2016-2018

作　　者：沙怡梅[1] 黄梨煜[1] 王睿煊 于博 姚一泓 喻颖杰[1] 赵耀[1] Sha Yimei;Huang Liyu;Wang Ruixuan;Yu Bo;Yao Yihong;Yu Yingjie;Zhao Yao(Beijing Center for Disease Control and Prevention,Beijing 100013,China;Peking Union Medical College,Beijing 100730,China)

机构地区：[1]北京市疾病预防控制中心,北京100013 [2]北京协和医学院,北京100730

出　　处：《卫生研究》2022年第6期969-974,共6页Journal of Hygiene Research

基　　金：国家重点研发计划(No.2016YFC1305201)。

摘　　要：目的评价北京市学龄儿童维生素D的营养状况。方法于2016年9月-2018年5月采用多阶段分层整群抽样抽取北京市5个区10所小学、10所初中、5所高中1385名学生,采用电化学发光免疫法测定血清中维生素D浓度。分析学龄儿童血清维生素D含量在城郊、年龄、体质指数、腰围、户外活动时间、近视情况下的分布情况,比较不同状况下学龄儿童维生素D的缺乏率、不足率。结果6~11岁和12~17岁学生血清中25(OH)D_(3)的含量[M(P25,P75)]分别为20.86(16.48,25.31)ng/mL和14.12(11.04,19.17)ng/mL,男生高于女生,12~17岁低于6~11岁,城区低于郊区,近视学生低于非近视学生,差异均有统计学意义(P<0.01)。户外活动时间大于等于2小时学生与低于2小时学生、正常体重和超重肥胖学生、正常腰围和腹型肥胖学生血清25(OH)D_(3)含量差异无统计学意义。学龄儿童维生素D缺乏率、不足率和缺乏不足率合计分别为18.8%(261人)、40.1%(556人)和59.0%(817人)。女生维生素D缺乏不足的情况比男生严重,12~17岁学生维生素D不足和缺乏的情况比6~11岁学生严重,城区学生维生素D缺乏和不足的情况比郊区严重,近视学生维生素D缺乏不足的情况比非近视严重,差异均有统计学意义(P<0.01)。户外活动时间大于等于2小时的学生维生素D缺乏不足情况与户外活动时间低于2小时学生,正常腰围和超重肥胖学生,正常体重和腹型肥胖学生不存在显著性差异。多因素Logistic分析显示,性别、年龄和城乡是维生素D缺乏及不足的显著影响因素。结论2016-2018年北京市女生维生素D不足和缺乏高于男生,12~17岁学生维生素D不足和缺乏比6~11岁严重;城市学生维生素D缺乏比农村严重,近视学生维生素D缺乏比非近视学生严重。OBJECTIVE To evaluate the nutritional status of vitamin D in school-age children in Beijing.METHODS The data was part of the monitoring data of Beijing in “Chinese Nutrition and Health Monitoring of Children and Nursing Mothers 2016-2017”. A total of 1385 students were recruited from 10 primary schools, 10 junior middle schools and 5 senior high schools. The concentrations of serum vitamin D were determined using electrochemiluminescence immunoassay. The distribution of serum vitamin D in school-age children was further described for different regions, age, body mass index(BMI), waistline, outdoor activity time and myopia. The prevalence of the insufficiency and deficiency of vitamin D was compared in different subgroups.RESULTS The median concentration of serum 25(OH)D_(3)[M(P25,P75)] of students aged 6-11 and 12-17 were 20.86(16.48,25.31) ng/mL and 14.12(11.04,19.17) ng/mL. The serum 25(OH)D_(3)of male school-age children was higher than that of female. The serum 25(OH)D_(3) of students aged 12-17 was lower than that of students aged 6-11. The serum 25(OH)D_(3)of urban students was lower than that of rural students, and the serum 25(OH)D_(3) of myopia students was lower than that of non-myopia students(P<0.01). There was no significant difference in serum 25(OH)D_(3) between students with outdoor activity time greater than or equal to 2 hours and students with less than 2 hours, normal weight and overweight and obese students, normal waist and abdominal obesity students. The vitamin D deficiency rate, insufficiency rate, insufficiency and deficiency rate of school-age children were 18.8%(261), 40.1%(556) and 59.0%(817). The vitamin D deficiency in girls was more serious than that in boys, and the vitamin D insufficiency and deficiency of students aged 12-17 were more serious than that of students aged 6-11. The vitamin D deficiency of students in urban areas was more serious than that in rural areas, and the vitamin D deficiency of myopia students was more serious than that of non-myopia(P<0.01). There was

关 键 词：营养健康监测 维生素D 学龄儿童 营养状况 

分 类 号：R153.2[医药卫生—营养与食品卫生学]