Pharmacological and analytical aspects of alkannin/shikonin and their derivatives:An update from 2008 to 2022  

作　　者：Kirandeep Kaur Rashi Sharma Atamjit Singh Shivani Attri Saroj Arora Sarabjit Kaur Neena Bedi 

机构地区：[1]Department of Pharmaceutical Sciences,Guru Nanak Dev University,Amritsar 143005,India [2]Department of Botanical and Environmental Sciences,Guru Nanak Dev University,Amritsar 143005,India

出　　处：《Chinese Herbal Medicines》2022年第4期511-527,共17页中草药（英文版）

摘　　要：Alkannin/shikonin(A/S)and their derivatives are naturally occurring naphthoquinones majorly found in Boraginaceae family plants.They are integral constituents of traditional Chinese medicine Zicao(roots of Lithospermum erythrorhizon).In last two decades significant increase in pharmacological investigations on alkannin/shikonin and their derivatives has been reported that resulted in discovery of their novel mechanisms in various diseases and disorders.This review throws light on recently conducted pharmacological investigations on alkannin/shikonin and their derivatives and their outputs.Various analytical aspects are also discussed and brief summary of patent applications on inventions containing alkannin/shikonin and its derivatives is also provided.

关 键 词：ALKANNIN NAPHTHOQUINONES patents SHIKONIN 

分 类 号：R285[医药卫生—中药学]