Visible Light-Promoted Amide Bond Formation via One-Pot Nitrone in Situ Formation/Rearrangement Cascade  

作　　者：Bao-Gui Cai Shuai-Shuai Luo Lin Li Lei Li Jun Xuan Wen-Jing Xiao 

机构地区：[1]Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials,Key Laboratory of Functional Inorganic Materials of Anhui Province,College of Chemistry and Chemical Engineering,Anhui University,Hefei,Anhui 230601 [2]Key Laboratory of Structure and Functional Regulation of Hybrid Materials,Ministry of Education,Anhui University,Hefei,Anhui 230601 [3]Key Laboratory of Pesticide and Chemical Biology,Ministry of Education,College of Chemistry,Central China Normal University,Wuhan,Hubei 430079

出　　处：《CCS Chemistry》2021年第11期2764-2771,共8页中国化学会会刊（英文）

基　　金：The authors acknowledge the National Natural Science Foundation of China(nos.21971001 and 21702001);the Start-up Grant from Anhui University for financial support of this work.

摘　　要：A green and sustainable synthetic strategy for amide bond formation utilizing a visible light-promoted nitrone formation/rearrangement cascade was developed.This method utilized visible light as the sole and clean energy source without the need for an exogenous photoredox catalyst or additive.Moreover,nitrones are generated in situ,bypassing the isolation process and producing only nitrogen gas as a byproduct.The synthetic value of this protocol has potential applications in the syntheses of amides containing important natural products and drugbased complex molecules.

关 键 词：AMIDES visible light CARBENE photocascade REARRANGEMENT 

分 类 号：O62[理学—有机化学]