葛根异黄酮组成、结构及功效机制研究进展  

Progress in Research on Composition,Structure,Functions and Mechanism of Action of Radix Puerariae Isoflavones

作　　者：曾文燊 黄达荣 谢斯威 杜冰[1] 黎攀 ZENG Wenshen;HUANG Darong;XIE Siwei;DU Bing;LI Pan(School of Food Science,South China Agricultural University,Guangzhou 510642,China;School of Mathematics and Informatics,South China Agricultural University,Guangzhou 510642,China)

机构地区：[1]华南农业大学食品学院,广东广州510642 [2]华南农业大学数学与信息学院,广东广州510642

出　　处：《食品科学》2023年第1期353-361,共9页Food Science

基　　金：财政部和农业农村部:国家现代农业产业技术体系资助(CARS-21)。

摘　　要：葛根是我国重要的药食两用食品,在我国有着丰富的产量和广大的受众人群。异黄酮类物质是葛根中含量最丰富、功效最多的活性成分,本文全面综述葛根异黄酮的组成、结构,系统阐述其降“三高”、抗氧化、解酒护肝、缓解绝经性骨质疏松、改善认知等功效及作用机制,分析葛根异黄酮研究的热点、存在的问题以及其对相关药物与食品开发的重要意义,为葛根基础研究与相关成果转化提供一定的思路和指导。Radix Puerariae(RP)is an important medicinal and edible food in China.The country has an abundant RP output and a large number of RP consumers.Isoflavones are the most abundant and bioactive ingredients in RP.This article comprehensively reviews the composition and structure of isoflavones from RP,and systematically expounds their functions such as anti-hypertension,anti-hyperlipidemia,anti-hyperglycemia and antioxidant activity,alleviating a hangover,liver protection,alleviating post-menopausal osteoporosis and improving cognition as well as the underlying mechanism of action.The current research hotspots and problems existing in the field of research on RP isoflavones and their significance to the development of drugs and functional foods containing RP isoflavones are also proposed.We believe that this review will provide useful ideas and guidance for the basic research on RP and the commercialization of research achievements in this field.

关 键 词：葛根 异黄酮 活性成分 机制 葛根素 

分 类 号：TS201.4[轻工技术与工程—食品科学]