曲酸洗手液研制  

Development of Kojic Acid Hand Sanitizer

作　　者：李镇江 杨志刚 叶莉 郑又铭 饶航 曾方塬 陈静 杨学昭 江源钢 李星 唐晓芳 LI Zhenjiang;YANG Zhigang;YE Li;ZHENG Youming;RAO Hang;ZENG Fangyuan;CHEN Jing;YANG Xuezhao;JIANG Yuangang;LI Xing;TANG Xiaofang(Sichuan Food and entation Industry Research Design Institute Co.,Ltd.,Chengdu,Sichuan 611130,China;Chengdu Jinkai Biology Engineering Co.,ltd.,Chengdu,Sichuan 611130,China;College of Biotechnology,Tianjin University of Science&Technology,Tianjin 300457,China)

机构地区：[1]四川省食品发酵工业研究设计院有限公司,四川成都611130 [2]成都金开生物工程有限公司,四川成都611130 [3]天津科技大学生物工程学院,天津300457

出　　处：《中国洗涤用品工业》2023年第1期21-28,共8页China Cleaning Industry

基　　金：四川省科技计划项目(No:2020ZHCG0091)。

摘　　要：研制了一款以曲酸、脂肪醇聚氧乙烯醚硫酸钠(AES)、椰油酰胺丙基甜菜碱(CAB-35)和月桂基葡糖苷(APG)为原料的洗手液。以洗手液性能和抑菌效果为指标,通过单因素实验和正交实验优化筛选出曲酸洗手液配方。结果表明:优化后的曲酸洗手液配方为AES 6%,CAB-356%,APG 9%,EDTA-2Na 0.1%,甘油1.0%,曲酸1.25%,氯化钠1.5%,pH 6,该配方经性能测定发泡力为109.55 mm,总活性物含量为12.33%,黏度为4266.7 mPa·s,具有抑菌作用。The hand sanitizer with raw materials of kojic acid, AES, CAB-35 and APG was developed. Methods: The formulation of kojic acid hand sanitizer was optimized and screened by single factor test and orthogonal experiment with the performance and antibacterial effect of hand sanitizer as indexes. The results showed that the optimized formulation of kojic acid hand sanitizer was composed of 6% AES, 6% CBA-35, 9% APG, 0.1% EDTA-2Na, 1.0% glycerol, 1.25% kojic acid and 1.5% sodium chloride. The pH value of the hand sanitizer was 6. The foaming power of this formulation is 109.55 mm, the total active substance content is 12.33%,the viscosity is 4266.7 mPa·s, and it has bacteriostatic effect.

关 键 词：洗手液 抑菌 正交实验 曲酸 

分 类 号：TQ649.6[化学工程—精细化工]