Effects of areca nut consumption on cell differentiation of osteoblasts, myoblasts, and fibroblasts  

作　　者：YUNG-FU CHANG 

机构地区：[1]Department of Biomedical Science and Environmental Biology,Kaohsiung Medical University,Kaohsiung,807,Taiwan [2]Department of Medical Research,Kaohsiung Medical University Hospital,Kaohsiung,807,Taiwan [3]Translational Research Center of Neuromuscular Diseases,Kaohsiung Medical University Hospital,Kaohsiung,807,Taiwan

出　　处：《BIOCELL》2023年第2期283-287,共5页生物细胞（英文）

基　　金：the funding provided by the Ministry of Science and Technology,Taiwan(108-2314-B-037-075);the Kaohsiung Medical University Research Foundation(KMU-M103001,KMU-M104003,KMU-TP104PR16).

摘　　要：Areca nut is used worldwide as a hallucinogenic addicting drug along the tropical belt.Arecoline,a toxic compound,is the most important alkaloid in areca nuts.The adverse effects of oral uptake and chewing of areca nut are well known.For example,the possibility of cancer caused by chewing areca nuts is widely discussed.Chewing areca nut has other adverse effects on other organs,including abnormal cell differentiation,oral cancer,and several other diseases.The use of areca nut is also associated with low birthweight.Skeletal musculature is the largest organ in the body and is attached to the bones.During embryo development,the differentiation of bone and muscle cells is critical.In this article,we reviewed the effects of areca nut and arecoline on embryonic cell differentiation,particularly osteoblasts,myoblasts,and fibroblasts.

关 键 词：Areca nut Cell differentiation OSTEOBLAST MYOBLAST FIBROBLAST 

分 类 号：R58[医药卫生—内分泌]