Case report:MPN-eo with balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11),responding to low dose imatinib  

作　　者：Karolien Beel Geneviève Ameye Wim De Kelver Lucienne Michaux 

机构地区：[1]Centre of Human Genetics,University Hospitals Leuven and KU Leuven,Leuven,Belgium

出　　处：《Discussion of Clinical Cases》2021年第3期1-3,共3页临床病例讨论杂志（英文版）

摘　　要：We present a young patient with a rare eosinophilic myeloproliferative neoplasm MPN-eo with a balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11).This fusion gene was reported in only one other case in 2015.A personalized molecular test was developed with the diagnostic material of the patient.Our patient is in complete cytogenetic and molecular remission under low dose imatinib,two years after treatment initiation.

关 键 词：EOSINOPHILIA MPN PDGFRB and MPRIP IMATINIB 

分 类 号：R73[医药卫生—肿瘤]