多甲氧基黄酮的化学合成研究进展  

Reviews in Chemical Synthesis of Polymethoxy Flavonoids

作　　者：陈梦钞 张玲桔 王蒙颖 郑赟 吴春艳 CHEN Mengchao;ZHANG Lingju;WANG Mengying;ZHENG Yun;WU Chunyan(Taizhou Vocational College of Science&Technology,Taizhou 318020,China;Zhejiang Taizhou Yiguan Food Co.,Ltd.,Taizhou 318020,China)

机构地区：[1]台州科技职业学院,浙江台州318020 [2]浙江台州一罐食品有限公司,浙江台州318020

出　　处：《食品安全导刊》2022年第30期171-173,共3页China Food Safety Magazine

基　　金：2022年浙江省大学生科技创新活性暨新苗人才计划(No.2022R482A001)。

摘　　要：多甲氧基黄酮是柑橘中的一种特殊成分,具有抗炎、抗癌、抗动脉粥样硬化和抗氧化等功效。因天然多甲氧基黄酮提取工作量大、时间长、成本高,因此研究其合成方法具有重要的临床应用价值。本文综述了铜催化法、轻醛缩合法、Baker-Venkataraman重排法等合成方法,以期提高合成多甲氧基黄酮的效率。Polymethoxyflavonoids is a special component in citrus, which has many functions such as anti inflammation, anti-cancer, anti atherosclerosis, anti-oxidation and so on. Because of the heavy workload, long time and high cost of extracting natural polymethoxyflavones, it is of great clinical value to study their synthesis methods.In this paper, the synthesis methods such as copper catalysis, light aldehyde condensation and Baker-Venkataraman rearrangement are reviewed in order to improve the efficiency of synthesis of polymethoxyflavones.

关 键 词：多甲氧基黄酮 铜催化法 轻醛缩合法 Baker-Venkataraman重排法 

分 类 号：TS201.2[轻工技术与工程—食品科学]