Research progress of artesunate in diabetes and its complications  

作　　者：Yuan-Hui Guo Lu-Lu Chen Ying LI Jia-Jia Duan Chuan-Xin Liu Hong-Wei Jiang 

机构地区：[1]Endocrine and Metabolic Disease Center,First Affiliated Hospital,College of Clinical Medicine of Henan University of Science and Technology,Medical Key Laboratory of Hereditary Rare Diseases of Henan,Luoyang Sub-center of National Clinical Research Center for Metabolic Diseases,Luoyang 471003,China [2]College of Clinical Medicine of Henan University of Science and Technology,Department of Pharmacy First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471003,China [3]College of Clinical Medicine of Henan University of Science and Technology,Laboratory Department of the First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471003,China

出　　处：《Traditional Medicine Research》2023年第5期44-51,共8页TMR传统医学研究

摘　　要：Diabetes is a metabolic disease characterized by abnormally elevated blood glucose levels.Persistent hyperglycemia leads to diabetic nephropathy,diabetic retinopathy,diabetes with periodontal disease and other diabetic complications.These diseases have become the main causes of disability and death in diabetic patients.Artesunate is well known as an antimalarial drug for controlling malaria symptoms.Current studies have shown that artesunate improves diabetes and its complications by protecting islet cells,improving glucose and lipid metabolism,anti-inflammatory and immune regulation.Based on the research status in recent years,this paper focuses on the mechanism of artesunate in diabetes and its complications,to provide a theoretical basis for future diabetes research.

关 键 词：ARTESUNATE DIABETES diabetic complications islet cells glycolipid metabolism ANTI-INFLAMMATORY IMMUNOREGULATION 

分 类 号：R58[医药卫生—内分泌]