IMMUNOREGULATION

作品数：78被引量：270H指数：9
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相关领域：医药卫生更多>>
相关机构：广州中医药大学哈尔滨医科大学苏州大学更多>>
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Indole-3-propionic acid enhances growth performance and reduces diarrhea via modulating redox status and intestinal inflammation in weaned piglets
《Animal Nutrition》2024年第4期240-247,共8页Dongxu Ming Xincong Xu Xianren Jiang Yanpin Li Wenjuan Sun Jiangbo Xiang Mingyuan Huang Yu Pi Xilong Li 
financially supported by the Science and Technology Program of Shijiazhuang City(236490539A);the China Postdoctoral Science Foundation(2023M730594);the Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences(CAAS-ZDRW202305);the Agricultural Science and Technology Innovation Program of the Feed Research Institute of the Chinese Academy of Agricultural Sciences(CAASIFR-ZDRW202302).
Indole-3-propionic acid(IPA)has anti-inflammatory properties,which can be beneficial for weaned piglets with underdeveloped immune systems.The study explores the impact of IPA supplementation on growth performance,oxi...
关键词：Indole-3-propionic acid IMMUNOREGULATION ANTIOXIDATION Intestinal health PIGLET 
Cell therapy for end-stage liver disease:Current state and clinical challenge
《Chinese Medical Journal》2024年第23期2808-2820,共13页Lin Zhang Yuntian Deng Xue Bai Xiao Wei Yushuang Ren Shuang Chen Hongxin Deng 
supported by grants from the National Key R&D Program of China grant(No.2022YFA1105602);the technology Major Project in Sichuan Province of China(No.2022ZDZX0024);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYGD23023).
Liver disease involves a complex interplay of pathological processes,including inflammation,hepatocyte necrosis,and fibrosis.End-stage liver disease(ESLD),such as liver failure and decompensated cirrhosis,has a high m...
关键词：Cell therapy End-stage liver disease Cell transplantation Liver regeneration FIBROSIS IMMUNOREGULATION 
Injectable immunoregulatory hydrogels sequentially drive phenotypic polarization of macrophages for infected wound healing被引量：1
《Bioactive Materials》2024年第11期193-206,共14页Yuxiang Wang Chen Zhou Zhulian Li Gong Li Yaping Zou Xing Li Peiyang Gu Jingyi Liu Lang Bai Hong Yan Jie Liang Xingdong Zhang Yujiang Fan Yong Sun 
National Key R&D Project of China(No.2022YFC2401800);National Natural Science Foundation of China(32071352 and 32271419).
Regulating macrophage phenotypes to reconcile the conflict between bacterial suppression and tissue regeneration is ideal for treating infectious skin wounds. Here, an injectable immunoregulatory hydrogel (SrmE20) tha...
关键词：Sequential immunoregulation Macrophage phenotypic polarization Injectable hydrogel Infected wounds 
Turning foes to friends:Advanced“in situ nanovaccine”with dual immunoregulation for enhanced immunotherapy of metastatic triple-negative breast cancer被引量：1
《Bioactive Materials》2024年第9期612-629,共18页Ze Wang Tong Sha Jinwei Li Huanyu Luo Annan Liu Hao Liang Jinbiao Qiang Lei Li Andrew K.Whittaker Bai Yang Hongchen Sun Ce Shi Quan Lin 
supported by the National Key Research and Development Program of China(2022YFC2504200);the National Natural Science Foundation of China(Nos.82270959 and 81970903);the Natural Science Foundation of Jilin Province(No.SKL202302002);the Key Research and Development Project of Jilin Provincial Science and Technology Department(Nos.20210204142YY);the Jilin University Norman Bethune Program(No.2023B28);the Fundamental Research Funds for the Central Universities,the Natural Science Foundation of Liaoning Province(No.2022-BS-123);the Science and Technology Project of Shenyang(No.21-173-9-34);“Medical+X”Interdisciplinary Innovation Team“Announcement and Leadership”Construction Project(2022JBGS08).
As a“cold tumor”,triple-negative breast cancer(TNBC)exhibits limited responsiveness to current immunotherapy.How to enhance the immunogenicity and reverse the immunosuppressive microenvironment of TNBC remain a form...
关键词：Metastatic triple-negative breast cancer In situ nanovaccine Immunogenic cell death Dual immunoregulation Synergistic therapy 
Bioactive compounds in Hericium erinaceus and their biological properties:a review
《Food Science and Human Wellness》2024年第4期1825-1844,共20页Yue Qiu Genglan Lin Weiming Liu Fuming Zhang Robert J.Linhardt Xingli Wang Anqiang Zhang 
supported by the fund from Natural Science Foundation of Zhejiang Province,China(LY17C200017)。
Hericium erinaceus is a nutritious edible and medicinal fungi,rich in a variety of functional active ingredients,with various physiological functions such as antioxidation,anticancer,and enhancing immunity.It is also ...
关键词：Hericium erinaceus Bioactive compounds Biological activities ANTIOXIDATION NEUROPROTECTION IMMUNOREGULATION 
Dual-functional microneedle with programmatic regulation of macrophage for autoimmune psoriasis treatment
《Nano Research》2024年第8期7436-7448,共13页Ze Qiang Zhao Bo Zhi Chen Jia Li Gan Yun Hao Feng Ling Liang Lingyun Yu Zi Yi Wang Samin Abbaszadeh Mohammad-Ali Shahbazi Ruixing Yu Xin Dong Guo 
supported by National Natural Science Foundation of China(Nos.52161145410,52373126,and 52303173);the National Natural Science Foundation of China-Iran National Science Foundation joint grant(No.4001987);Beijing University of Chemical Technology-China-Japan Friendship Hospital Biomedical Translational Engineering Research Center Key Projects(No.XK2023-20);the longterm subsidy mechanism from the Ministry of Finance and the Ministry of Education of People's Republic of China.M.-A.S.acknowledges the financial support of the incentive and startersbeurs funds from the University of Groningen,Groningen,The Netherlands.
Modulating the immune microenvironment to establish sustained positive feedback within immune pathways represents a promising avenue for the treatment of autoimmunity.However,the precise and efficient delivery of ther...
关键词：MICRONEEDLE PSORIASIS M2 macrophage IMMUNOREGULATION 
Oxalate regulates crystal-cell adhesion and macrophage metabolism via JPT2/PI3K/AKT signaling to promote the progression of kidney stones
《Journal of Pharmaceutical Analysis》2024年第6期851-862,共12页Qianlin Song Chao Song Xin Chen Yunhe Xiong Ziqi He Xiaozhe Su Jiawei Zhou Hu Ke Caitao Dong Wenbiao Liao Sixing Yang 
supported by the National Natural Science Foundation of China(Grant Nos.:82070723,82270797);Nature Science Foundation of Hubei Province,China(Grant No.:2022CFC020).
Oxalate is an organic dicarboxylic acid that is a common component of plant foods.The kidneys are essential organs for oxalate excretion,but excessive oxalates may induce kidney stones.Jupiter microtubule associated h...
关键词：OXALATE Kidney stones JPT2 Crystal-cell adhesion IMMUNOREGULATION 
Differences in the effects and action modes of gut commensals against dextran sulfate sodium-induced intestinal inflammation
《Food Science and Human Wellness》2024年第3期1201-1211,共11页Dingwu Qu Zhennan Gu Saisai Feng Leilei Yu Fengwei Tian Hao Zhang Wei Chen Qixiao Zhai 
supported by the Natural Science Foundation of Jiangsu Province (BK20200084);The National Natural Science Foundation of China (U1903205 and 31972971);Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province。
Inflammatory bowel disease(IBD)is a complex relapsing inflammatory disease in the gut and is driven by complicated host-gut microbiome interactions.Gut commensals have shown different functions in IBD prevention and t...
关键词：Gut commensals Dextran sulfate sodium(DSS)colitis Intestinal barrier IMMUNOREGULATION 
Extracellular vesicles loaded dual-network bioactive sealant via immunoregulation and annulus fibrosus repair for intervertebral disc herniation被引量：1
《Journal of Materials Science & Technology》2024年第17期75-87,共13页Zetao Wang Haofei Li Huitong Luo Hao Wang Zemin Ling Dafu Chen Qi Feng Xiaodong Cao 
supported by the National Natural Science Foundation of China(Grant Nos.51873069,52272276,52073103,52203164);the Zhongshan Innovation Project of high-end Scientific Research Institutions(Grant No.2020AG020);the Key-Area Research and Development Program of Guangdong Province(No.2020B090924004);Beijing Municipal Health Commission(Grant Nos.BMHC-2018-4,BMHC-2019-9,PXM2020026275000002);the Postdoctoral Research Foundation of China(No.2022M711183).
Intervertebral disc herniation(IVDH)is a common manifestation of intervertebral disc degeneration(IVDD)characterized by inflammation that results in the rupture of the annulus fibrosus(AF)and her-niation of the nucleu...
关键词：Intervertebral disc herniation Extracellular vesicles Double-network hydrogel SEALANT IMMUNOREGULATION 
Research progress of artesunate in diabetes and its complications
《Traditional Medicine Research》2023年第5期44-51,共8页Yuan-Hui Guo Lu-Lu Chen Ying LI Jia-Jia Duan Chuan-Xin Liu Hong-Wei Jiang 
Diabetes is a metabolic disease characterized by abnormally elevated blood glucose levels.Persistent hyperglycemia leads to diabetic nephropathy,diabetic retinopathy,diabetes with periodontal disease and other diabeti...
关键词：ARTESUNATE DIABETES diabetic complications islet cells glycolipid metabolism ANTI-INFLAMMATORY IMMUNOREGULATION 
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