出 处:《中华行为医学与脑科学杂志》2022年第12期1086-1091,共6页Chinese Journal of Behavioral Medicine and Brain Science
基 金:芜湖市卫健委科研项目(WHWJ2021y071)。
摘 要:目的探讨认知情绪调节策略不同维度对青少年单相抑郁和双相抑郁的影响。方法2019年6月至2021年7月选取216名青少年抑郁障碍患者,其中单相抑郁组134例,双相抑郁组82例,同期选取正常对照组111人。采用汉密尔顿抑郁量表(Hamilton depression scale,HAMD)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)及认知情绪调节量表(cognitive emotion regulation questionnaire,CERQ)评估所有入组被试的情绪症状及认知情绪调节策略。采用SPSS 23.0对数据进行统计分析,统计方法使用Kruskal-Wallis秩和检验以及多元Logistic回归分析。结果三组被试在认知情绪调节策略各维度以及情绪症状上均差异有统计学意义(均P<0.01),双相抑郁组和单相抑郁组的自我责难[14.00(12.00,17.00)分,13.50(12.00,16.00)分,12.00(11.00,12.00)分]、反刍[15.00(12.00,19.00)分,14.00(12.00,17.00)分,12.00(10.00,13.00)分]、灾难化[13.00(11.00,17.00)分,12.00(9.00,16.00)分,8.00(6.00,12.00)分]得分显著高于正常对照组(P<0.01)。双相抑郁组的责难他人[11.00(8.75,13.25)分,9.00(8.00,12.00)分]得分显著高于正常对照组(P<0.01)。正常对照组的积极重新评价[12.00(12.00,15.00)分,11.00(8.75,13.00)分]得分显著高于单相抑郁组(P<0.01)。正常对照组的理性分析[10.00(8.00,12.00)分,12.00(10.00,13.00)分,12.00(10.00,13.25)分]得分显著低于单相抑郁和双相抑郁组(均P<0.01)。单相抑郁组和双相抑郁组HAMD[25.00(22.00,26.25)分,23.00(18.00,28.00)分,3.00(0,6.00)分]和HAMA[17.00(14.00,21.00)分,20.00(16.00,27.00)分,1.00(0,3.00)分]评分均显著高于正常对照组(均P<0.01)。多元Logistic回归分析表明,与正常对照组相比,自我责难、反刍、灾难化分别是单相抑郁(OR=1.19,95%CI=1.05~1.35;OR=1.17,95%CI=1.06~1.30;OR=1.14,95%CI=1.02~1.27)和双相抑郁(OR=1.30,95%CI=1.14~1.50;OR=1.21,95%CI=1.07~1.36;OR=1.13,95%CI=1.01~1.28)的风险因素,积极重新评价是单相抑郁(OR=0.83,95%CI=0.73~0.95)和双相抑郁(OR=0.8Objective To explore the impact of different dimensions of cognitive emotion regulation strategies on adolescents with unipolar depression and bipolar depression.Methods From June 2019 to July 2021,a total of 216 adolescents with depressive disorder were selected,including 134 patients in unipolar depression group,82 patients in bipolar depression group,and 111 normal controls were selected at the same time.Hamilton depression scale(HAMD),Hamilton anxiety scale(HAMA)and cognitive emotion regulation questionnaire(CERQ)were used to evaluate the emotional symptoms and cognitive emotion regulation strategies of all enrolled subjects.SPSS 23.0 was used for statistical analysis of the data.Kruskal-Wallis rank sum test and multiple Logistic regression analysis were used for statistical analysis.Results There were significant differences in the dimensions of cognitive emotion regulation strategies and emotional symptoms among the three groups(all P<0.01).The scores of self-blame(14.00(12.00,17.00),13.50(12.00,16.00),12.00(11.00,12.00)),rumination(15.00(12.00,19.00),14.00(12.00,17.00),12.00(10.00,13.00))and catastrophizing(13.00(11.00,17.00),12.00(9.00,16.00),8.00(6.00,12.00))in bipolar depression group and unipolar depression group were significantly higher than those in normal control group(all P<0.01).The score of blaming others(11.00(8.75,13.25),9.00(8.00,12.00))in bipolar depression group was significantly higher than that in normal control group(P<0.01).The score of positive reappraisal(12.00(12.00,15.00),11.00(8.75,13.00))in normal control group was significantly higher than that in unipolar depression group(P<0.01).The putting into perspective score(10.00(8.00,12.00),12.00(10.00,13.25),12.00(10.00,13.00))of normal control group was significantly lower than those of unipolar depression and bipolar depression group(both P<0.01).The scores of HAMD(25.00(22.00,26.25),23.00(18.00,28.00),3.00(0,6.00))and HAMA(17.00(14.00,21.00),20.00(16.00,27.00),1.00(0,3.00))both in unipolar depression group and bipolar depression grou
分 类 号:R749.4[医药卫生—神经病学与精神病学]
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