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作 者:Serafino Fazio Flora Affuso
机构地区:[1]Department of Internal Medicine,Federico II University of Naples,Napoli 80100,Italy [2]Independent Researcher,Home,Gallipoli 73014,Lecce,Italy
出 处:《World Journal of Meta-Analysis》2023年第1期1-4,共4页世界荟萃分析杂志
摘 要:The goals of global vaccination are to control,eliminate,or eradicate infectious diseases in a sustainable way that strengthens public health systems.Although the use of vaccines is essential for the control of epidemics,the vaccines against coronavirus disease 2019(COVID-19)proved to be inadequate to end the pandemic and thus are considered incomplete.These vaccines failed to prevent infection,so their primary purpose has been shifted to prevent severe disease and reduce hospitalizations and deaths.Therefore,we believe that all the strategies available to reduce transmission,hospitalizations and deaths due to COVID-19 will be put in place.It is reported that uncontrolled inflammation and thrombosis are the principal mechanisms for aggravation and death in patients with COVID-19.Unlike corticosteroids that should not be administered at the beginning of the symptoms for their immunosuppressive action,which could worsen the evolution of the disease,the usefulness of non-steroidal anti-inflammatory drugs in the early at-home treatment of the disease is becoming evident.
关 键 词:VACCINATION Non-steroidal anti-inflammatory drugs COVID-19 Early Treatment INDOMETHACIN HOSPITALIZATIONS
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