Biogenesis of autophagosomes from the ERGIC membrane system  

作　　者：Yaping Han Shulin Li Liang Ge 

机构地区：[1]The State Key Laboratory of Membrane Biology,Tsinghua University-Peking University Joint Center for Life Sciences,School of Life Sciences,Tsinghua University,Beijing 100084,China

出　　处：《Journal of Genetics and Genomics》2023年第1期3-6,共4页遗传学报（英文版）

基　　金：funded by Beijing Natural Science Foundation(JQ20028);the National Natural Science Foundation of China(32130023,91854114,32061143009);Ministry of Science and Technology of the People’s Republic of China(2019YFA0508602,2021YFA0804802)。

摘　　要：Introduction Macroautophagy(hereafter referred as autophagy)is a process of cellular self-degradation.In response to nutrient deprivation or other stimuli,a nascent double-membrane autophagosome,encapsulating intracellular materials or damaged organelles,is generated.The autophagosome is transported toward and eventually fuses with the lysosome(or the vacuole in yeast and plant cells).

关 键 词：ERGIC COPII vesicle Autophagosome biogenesis Autophagy ERES 

分 类 号：R36[医药卫生—病理学]