TREMble Before TREM2:The Mighty Microglial Receptor Conferring Neuroprotective Properties in TDP-43 Mediated Neurodegeneration  

作　　者：William A.Mills III Ukpong B.Eyo 

机构地区：[1]Brain Immunology and Glia Center,University of Virginia,Charlottesville,VA,22903,USA [2]Department of Neuroscience,University of Virginia,Charlottesville,VA,22903,USA [3]Robert M.Berne Cardiovascular Research Center,University of Virginia,Charlottesville,VA,22903,USA

出　　处：《Neuroscience Bulletin》2023年第1期163-166,共4页神经科学通报（英文版）

摘　　要：Microglia were long hailed as solely infammatory cells,and though they are responsible for the brain's immuneresponse,they perform a variety of neuroprotective func-tions including the clearance of cellular and toxic debris^([1]).One toxic molecule known to be cleared by microglia isthe protein aggregate found in Alzheimer's Disease(AD),amyloid-B.

关 键 词：protective DEGENERATION Alzheimer 

分 类 号：R741[医药卫生—神经病学与精神病学]